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Thoracolumbar corpectomy/spondylectomy for spinal metastasis: a pooled analysis comparing the outcome of seven different surgical approaches

机译:胸瘤术术/脊髓切除术:融合分析比较了七种不同手术方法的结果

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To compare surgical outcomes between seven different approaches for thoracolumbar corpectomy/spondylectomy in the setting of spinal metastasis. A systematic review of literature was performed including articles on corpectomy for thoracolumbar spinal metastasis. Data were extracted and sorted by surgical approach: en bloc spondylectomy (group 1), transpedicular (group 2), costotransversectomy (group 3), mini-open retropleural/retroperitoneal (group 4a), lateral extracavitary approach (group 4b), open transthoracic/transretroperitoneal (group 5), and thoracoscopic (group 6). Comparison of demographics, blood loss, directly procedure related complications, operating time, and postoperative improvement of pain. A total of 63 articles were included comprising data of 774 patients with various primary tumor entities. Mean age was 51.8years, 54% of patients were female, on average 1.46 levels were treated per patient, and mean follow-up was 1.59years. The following statistically significant findings were observed: Blood loss was lowest for the mini-open retropleural/retroperitoneal (917ml), thoracoscopic (1107ml) and transthoracic approach (1172ml) versus the posterior approach groups (1633 2261ml); directly procedure related complications were lowest for mini-open retropleural/retroperitoneal and thoracoscopic approach (0% each) versus 7 15% in the other groups; operating time was lowest in mini-open retropleural/retroperitoneal approach (184min) versus 300 588min in the other groups. Less invasive approaches (mini-open retropleural/retroperitoneal and thoracoscopic) not only had superior outcome in terms of blood loss and operating time, but also were shown to be safe techniques in cancer patients with low rates of procedure-related complications. These slides can be retrieved under Electronic Supplementary Material.
机译:在脊髓转移的设定中比较胸腔瘤术术/脊椎切除术的七种不同方法之间的手术结果。对文献进行了系统审查,包括关于胸腰椎转移的物质术文章。通过手术方法提取和分类数据:en Bloc纯血液切除术(第1组),血管分布(第2组),CostOtranseCectomy(第3组),迷你开放血液血液术(第4A组),横向骨干接近(第4B组),开放性/转基因(第5组)和胸腔镜(第6组)。人口统计,失血,直接程序相关并发症,操作时间和术后改善疼痛的比较。包含63篇文章,包括774例各种原发性肿瘤实体的数据。平均年龄为51.8岁,54%的患者是女性,平均每位患者治疗1.46水平,平均随访时间为1.59年。观察到以下统计学上显着的发现:迷你开放夹持/腹膜(917ml),胸腔镜(1107ml)和经线方法(1172ml)与后接近群体(16332261ml)的失血量最低(1172ml);直接程序相关并发症对于迷你开放的丧失术/腹膜和胸腔诊断方法(0%)与其他群体中的7 15%;在迷你开放夹持/腹膜内接近(184min)的工作时间最低(184分钟)与其他组300 588min。较少的侵入方法(迷你开放式夹持/腹膜内和胸腔镜)不仅在损伤和操作时间方面具有卓越的结果,而且还被证明是癌症患者的安全技术,该癌症患者患者患者患者患者。这些幻灯片可以在电子补充材料下检索。

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