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Factors associated with surgical approach and outcomes in cerebral palsy scoliosis

机译:与脑瘫脊柱侧凸的外科手术和结果相关的因素

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Neuromuscular scoliosis is often treated with posterior spinal fusion, with or without anterior release, and either a same-day or staged, 2-day procedure. We retrospectively reviewed 222 patients from a prospectively collected, multi-center database of patients with cerebral palsy scoliosis with 2-year follow-up. Baseline characteristics, perioperative, radiographic, and HRQoL measures were compared in six sub-analyses: (1) staged versus same-day surgeries, (2) posterior-only fusion (PSF) versus anterior posterior spinal fusion (APSF), (3) same-day versus staged PSF, (4) staged versus same-day APSF, (5) same-day PSF versus same-day APSF, (6) staged PSF versus staged APSF. Staged patients had larger curves and more pelvic obliquity, longer anesthesia and surgical times, longer hospital and ICU stays (p0.001), and more days intubated (p=0.021). The staged PSF group had larger curves (p=0.006), longer anesthesia (p=0.020) and surgeries (p=0.007), hospital (p=0.009) and ICU stays (p=0.028) compared to same-day PSF. The staged APSF group had longer hospital (p0.001) and ICU stays (p=0.004) and anesthesia and surgeries (p0.001). Same-day APSF was associated with larger curves (p0.002), longer anesthesia (p=0.012) and surgeries (p=0.042), greater residual curves (p=0.035), and greater absolute correction (p=0.007) compared to same-day PSF. The staged APSF group had longer anesthesia times (p0.001) compared to the staged PSF group. No sub-analysis revealed significant differences in baseline characteristics, complications, or HRQoL. Staged and circumferential approaches tend to be used for greater deformity, but were not associated with superior deformity correction, and were associated with longer operative time, hospital stays, ICU stays, and days intubated. However, for the most severe deformity, other patient factors may play more important roles in treatment decisions given that patients treated with a staged PSF or an APSF, whether staged or not, were similar at baseline. III. These slides can be retrieved under Electronic Supplementary Material.
机译:神经肌病患者通常用后脊柱融合,有或没有前释放的脊髓融合,以及同一天或分阶段,2天的步骤。我们回顾性地审查了来自脑瘫患者的前瞻性多中心数据库222名患者,其脑瘫患者患有2年的随访。基线特征,围手术期,射线照相和HRQOL措施在六个分析中进行了比较:(1)阶段与同日度手术,(2)唯一的融合(PSF)与前后脊柱融合(APSF),(3)当天与分阶段PSF,(4)与同阶段APSF,(5)当天PSF与Adit-Day APSF,(6)分阶段PSF与暂存的APSF相比。分期患者具有较大的曲线和更多的骨盆倾斜,较长的麻醉和外科时间,较长的医院和ICU停留(P <0.001),并预热时间(p = 0.021)。分阶段的PSF组具有较大的曲线(P = 0.006),长时间麻醉(P = 0.020)和手术(P = 0.007),与当天PSF相比,医院(P = 0.009)和ICU停留(P = 0.028)。分期的APSF组具有更长的医院(P <0.001)和ICU停留(P = 0.004)和麻醉和手术(P <0.001)。当天(p <0.002),较长麻醉(P = 0.012)和手术(p = 0.042),较大的绝对校正(P = 0.035),以及更大的绝对校正(P = 0.035),以及更大的绝对校正(P = 0.007),较长当天psf。与分阶段的PSF组相比,分期的APSF组具有较长的麻醉时间(P <0.001)。没有次分析显示基线特征,并发症或HRQOL的显着差异。阶段和周向方法倾向于用于更大的畸形,但与优异的畸形校正无关,并且与较长的操作时间,医院住宿,ICU住宿和天管有关。然而,对于最严重的畸形,其他患者因素可能在治疗决策中发挥更重要的作用,因为用分阶段的PSF或APSF治疗,无论是否阶段,是否在基线上相似。 III。这些幻灯片可以在电子补充材料下检索。

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