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Primary ocular sporotrichosis with granulomatous conjunctivitis

机译:原发性眼孢子孢子瘤和肉芽肿性结膜炎

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Sporotrichosis is an infection which is caused by the dimorphic fungus Sporothrix schenckii . Primary ocular sporotrichosis is uncommon in non-endemic areas and may be easily misdiagnosed, leading to a delay in initiation of treatment. In this case report, a 15-year-old girl, who is a post renal transplant patient presented with left eye swelling and localized redness at the medial canthal region. She was initially treated with topical antibiotics but there was no improvement. The addition of topical steroids led to the development of multiple nodules with central ulceration. Examination of the left eye showed granulomatous conjunctivitis. The features were suggestive of sporotrichosis and she was empirically started on oral itraconazole. A biopsy of the lesion showed caseating granulomatous inflammation and fungal PCR tested positive for Sporothrix schenckii . Her symptoms and clinical findings completely resolved after 3 weeks on itraconazole; however, her liver function deteriorated, and patient opted to discontinue the medication.
机译:Sporotrichosis是一种感染,它是由二晶真菌孢子素Schenckii引起的感染。在非流行区域中,原发性眼孢子孢菌病是罕见的,并且可能很容易误诊,导致治疗开始延迟。在本案中,一名15岁的女孩是一名15岁的女孩,他是肾脏移植患者,呈现出左眼肿胀和内侧坎卡尔地区的局部发红。她最初用局部抗生素治疗,但没有改善。局部类固醇的添加导致了具有中央溃疡的多个结节的发展。对左眼的检查显示肉芽肿性结膜炎。该特征旨在刺激孢子素病,并且在口服伊丙酮上的经验开始。病变的活组织检查显示孢子瘤炎症和真菌PCR对孢子素Schenckii的阳性。在Itraconazole 3周后,她的症状和临床结果完全解决;然而,她的肝功能恶化,患者选择停止药物。

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