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Effects of Sperm Parameters on Pregnancy Rate in Patients Undergoing Intrauterine Insemination

机译:精子参数对宫内授精患者妊娠率的影响

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OBJECTIVE: In this study, the effects of sperm parameters on the success of intrauterine insemination were investigated. STUDY DESIGN: The data from 309 infertile couples who were admitted between 2012-2018 without a female factor were analyzed retrospectively and included in the study. After the administration of gonadotropin and hCG (5000-10000 IU), single insemination was performed in 36-40 hours in all cycles. All couples underwent routine infertility screening. The relationship between sperm parameters (motility, morphology, sperm count), patient age, duration of infertility with intrauterine insemination success was evaluated.RESULTS: There was no statistically significant difference between the two groups in terms of mean age and age related-parity. There was no statistically significant difference between male ages, liquefaction, and sperm volumes between the two groups (p=0.898, p=0.448, p=0.651). Before washing; There was a statistically significant difference between the sperm concentration, percentage of total motile sperm, percentage of progressive motility sperm, percentage of normal sperm morphology, and total sperm count between the two groups (p=0.0001, p=0.0001, p=0.0001, p=0.0001, p=0.0001). After sperm washing; the results were similar to those obtained before washing. While statistically significant difference was observed between sperm volume and sperm concentrations (p=0.023, p=0.018), no significant difference was observed between the two groups in total sperm count (p=0.612).CONCLUSION: As a result, during the application of intrauterine insemination to infertile couples, total motile sperm count, progressive motility sperm count ratio and high sperm ratio with normal morphology used in order to increase pregnancy success can be considered as criteria that increase the chances of success.
机译:目的:在这项研究中,研究了精子参数对宫内节制授精成功的影响。研究设计:从2012 - 2018年在没有女性因素的情况下在没有女性因素的情况下录取的309次不孕夫妇的数据被回顾性地分析并包括在研究中。促进促性腺激素和HCG(5000-10000 IU)后,在所有循环中在36-40小时内进行单授精。所有夫妻都经过常规不孕症筛查。评估精子参数(运动,形态,精子计数),患者年龄,患有子宫内授精成功的不孕症之间的关系。结果:两组在平均年龄和年龄相关奇偶阶段之间没有统计学上显着差异。两组之间的男性年龄,液化和精子体积没有统计学上显着差异(P = 0.898,P = 0.448,P = 0.651)。洗完之前;精子浓度,总运动精子的百分比,渐进运动精子的百分比,正常精子形态的百分比,两组之间的总精子计数之间存在统计学上的显着差异,两组之间的总精子计数(p = 0.0001,p = 0.0001,p = 0.0001, p = 0.0001,p = 0.0001)。精子洗涤后;结果与洗涤前获得的结果类似。在精子体积和精子浓度之间观察到统计学上有显着差异(P = 0.023,P = 0.018),两组在总精子计数(P = 0.612)之间没有显着差异(p = 0.612)。结论:因此,在施用期间在宫内生精中对不孕夫妻,总动机精子计数,渐进运动精子计数比和高精子比率,以增加妊娠成功的正常形态可以被视为增加成功机会的标准。

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