首页> 外文期刊>Frontiers in Public Health >SARS-CoV-2 Infections in the World: An Estimation of the Infected Population and a Measure of How Higher Detection Rates Save Lives
【24h】

SARS-CoV-2 Infections in the World: An Estimation of the Infected Population and a Measure of How Higher Detection Rates Save Lives

机译:SARS-COV-2在世界上感染:对受感染的人口的估计和衡量检测利率如何拯救生命

获取原文
           

摘要

This paper provides an estimation of the accumulated detection rates and the accumulated number of infected individuals by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Worldwide, on July 20, it has been estimated above 160 million individuals infected by SARS-CoV-2. Moreover, it is found that only about 1 out of 11 infected individuals are detected. In an information context in which population-based seroepidemiological studies are not available, this study shows a parsimonious alternative to provide estimates of the number of SARS-CoV-2 infected individuals. By comparing our estimates with those provided by the population-based seroepidemiological ENE-COVID study in Spain, we confirm the utility of our approach keeping in mind that from the public health point of view, it is preferable to be vaguely right than precisely wrong. Then, by means of a cross-country regression, we investigated if differences in detection rates can explain differences in the cumulative number of deaths. The hypothesis investigated in this study is that higher levels of detection of SARS-CoV-2 infections, which includes asymptomatic population, and those in their early stages of the infection (which are more infectious) can reduce the risk exposition of susceptible population with relatively higher risk of death. Our results show that, on average, detecting 5 instead 35 percent of the infections multiplies the number of deaths by a factor of about 6. Using this result, we estimated that 120 days after the pandemic outbreak, if the US would have tested with the same intensity as South Korea, about 85,000 out of their 126,000 reported deaths could have been avoided.
机译:本文通过新型严重急性呼吸综合征冠状病毒2(SARS-COV-2)估计累积的检测率和受感染的个体累积数量的估计。全球,7月20日,估计超过160万人被SARS-COV-2感染的人。此外,发现仅检测11个感染个体中的约1个。在不可用的基于人群的血液化学研究的信息上下文中,该研究表明了一种解析的替代方案,提供了SARS-COV-2受感染的个体数量的估计。通过将我们的估算与西班牙人口的血清术eNE-Covid研究提供的估计进行比较,我们确认了我们的方法牢记,从公共卫生的角度来看,优选含糊不清而当。然后,通过越野回归,我们调查了检测率的差异可以解释累积死亡人数的差异。本研究中研究的假设是较高水平的SARS-COV-2感染程度,包括无症状的人群,以及它们的早期阶段的感染(更传染性)可以减少易感人群的风险阐述相对较高的死亡风险。我们的结果表明,平均检测5而不是35%的感染量将死亡人数乘以约6.使用这一结果,我们估计大流行爆发后120天,如果美国会与之测试与韩国相同的强度,大约85,000名据报道的死亡人数约为85,000人。

著录项

获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号