Epidural anesthesia minimizes perioperative pain in dogs. It is considered that epidural solution dispersion in cadavers is similar to alive dogs. The objective of the anatomical study was to compare the dispersion of 0.2 mL/kg 0.25% bupivacaine and iohexol via lumbar epidural (L1-L2) under fluoroscopic guidance in 10 thawed cadavers (GC) and 13 female dogs (G0.25) (5-15 kg; body score 4/5). The objective of the clinical study was to evaluate postoperative analgesic consumption and sedation for 6 hours after extubation of dogs submitted to ovariohysterectomy when using 0.25% (G0.25; n=10) bupivacaine with the intraoperative use of fentanyl (GF; n=10). Parametric data were compared by the t-test and non-parametric data by the Mann Whitney test. Pain and sedation scores were evaluated over time by the Friedman test, followed by the Dunn test. Alive dogs presented greater epidural dispersion (17 ± 3 vertebrae) than thawed cadavers (11 ± 4 vertebrae; p=0.002). All dogs treated with fentanyl and only one dog treated with 0.25% epidural bupivacaine presented pain scores above the cut-off point of the Glasgow Composite Measure Pain Scale Short-Form (GCMPS-SF) and required postoperative rescue analgesia up to 6 hours after extubation. The sedation score was higher at all postoperative moments compared to preoperative moments in the G0.25 and GF, except for evaluations performed at 5 and 6 hours after extubation in the GF. Greater sedation was observed immediately after extubation in the GF compared to the G0.25, and there was greater sedation in the G0.25 compared to the GF from 3 to 6 hours after extubation. The conclusion of the anatomical study was that L1-L2 epidural bupivacaine dispersion is lower in canine thawed cadavers than in alive dogs. Conclusion of the clinical study was that lumbar epidural anesthesia improved postoperative analgesia and produced longer postoperative sedation when compared to fentanyl.
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机译：硬膜外麻醉最大限度地减少狗的围手术期疼痛。据认为，尸体中的硬膜外溶液分散与活犬相似。解剖学研究的目的是将0.2ml / kg 0.25％Bupivacaine和碘豆醇的分散体通过腰椎（L1-L2）在10次解冻的尸体（GC）和13名雌狗（G0.25）（5 -15公斤;身体得分4/5）。临床研究的目的是在使用0.25％（G0.25; N = 10）Bupivacain与芬太尼的术中使用0.25％（G0.25; n = 10）露天刚（GF; n = 10）时，评估术后镇痛消费和镇静术后6小时。 ）。通过Mann Whitney测试通过T-Test和非参数数据进行参数化数据。弗里德曼试验随着时间的推移，随后评估了疼痛和镇静分数，其次是DUNN测试。活犬呈现出比解冻的尸体更大的硬膜外分散体（17±3°）（11±4椎体; p = 0.002）。所有用芬太尼治疗的狗均用0.25％硬膜外蟾蜍处理的一只狗呈现在格拉斯哥复合措施疼痛规模短型（GCMPS-SF）的截止点上方的疼痛评分，并在拔管后长达6小时的术后救援镇痛。 。与G0.25和GF中的术前瞬间相比，镇静剂在术后时刻较高，除了在GF中拔管后5和6小时进行的评价。在GF中拔管后立即观察到更大的镇静与G0.25相比，G0.25中的镇静剂较大，与拔管后3至6小时相比。解剖学研究的结论是，犬解冻尸体中的L1-L2硬膜外海绵状物分散比在活犬中较低。结论临床研究是腰椎麻醉改善术后镇痛，与芬太尼相比，术后镇静较长。
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