TO THE EDITOR: I read with great interest the article by Goyal et al.1 (Goyal A, Yolcu YU, Goyal A, et al. The T2-FLAIR–mismatch sign as an imaging biomarker for IDH and 1p/19q status in diffuse low-grade gliomas: a systematic review with a Bayesian approach to evaluation of diagnostic test performance. Neurosurg Focus. 2019;47[6]:E13). The authors made a good attempt at highlighting an imaging feature “T2-FLAIR–mismatch sign” described by Patel et al.2 in diagnosing IDH mutation and 1p/19q non-codeleted gliomas (IDH mutant astrocytomas). However, I was surprised by a number of inaccuracies in this manuscript that potentially seriously undermine the impact of a reputable journal such as Neurosurgical Focus and also have the potential to mislead future publications on this topic if not corrected. One of the most glaring mistakes is citing a wrong reference for the T2-FLAIR–mismatch sign. This sign was first published by Patel et al.2 (reference 24 from the publication in question) and later validated by Broen et al.3 (reference 4 from the publication in question). When the authors described the sign in the second paragraph of the introduction, they wrongly cited the validation study as the original publication. Another error by the authors is in the legend for Fig. 1, which mentions a WHO grade III anaplastic astrocytoma with IDHmut-Codel. Astrocytomas in general and also the gliomas that show T2-FLAIR–mismatch sign are IDHmut-Noncodel gliomas.
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机译：到编辑：我很兴趣地欣赏Goyal et al.1的文章（Goyal A，Yolcu Yu，Goyal A等人。T2-Flair-Mismatch标志为IDH和1P / 19Q状态的成像生物标志物低级Gliomas：具有贝叶斯探测诊断测试性能的贝叶斯方法的系统审查。神经科学焦点。2019; 47 [6]：E13）。作者在诊断IDH突变和1P / 19Q非编辑胶质瘤（IDH突变星形星形细胞瘤）中，突出了Patel等Al.2描述的成像功能“T2-Flair-Mismatch标志”的成像功能“T2-Flair-Mismatch标志”。但是，我对这一稿件的许多不准确性感到惊讶，可能严重破坏了众所周知的杂志的影响，如神经外科焦点，并且如果没有纠正，也有可能误导未来出版物。最耀眼的错误之一旨在引用T2-Flair-Mismatch标志的错误参考。该标志首次由Patel et al.2公布（来自职有的出版物的参考文献24），后来由Broen et al.3验证（来自题为的发表）。当作者描述了介绍第二段的标志时，他们错误地将验证研究作为原始出版物。作者的另一个错误是图4的图例。1，其提及谁具有IDhmut-codel的III级血管紧节胶质细胞瘤。星形细胞瘤通常以及显示T2-Flair-Mismatch标志的胶质瘤是Idhmut-Noncodel Gliomas。
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