Background/Aims:Sarcopenia and erectile dysfunction (ED) are associat ed with poor health and quality of life in older men. We investigate the association between sarcopenia and severe ED in community-dwelling older men.Methods:We prospectively assessed sarcopenia and ED in 519, community-dwelling, older men (mean age, 74.0) in Pyeongchang, Korea, in 2016 to 2017. Sarcopenia was based on muscle mass, grip strength, and gait speed according to the Asian Working Group consensus algorithm. Severe ED was defined as 5-item International Index of Erectile Function questionnaire score under 8. Lo gistic regressions were used to study associations between incident severe ED and sarcopenia, after adjusting age, cardiovascular risk factors, depression, and poly pharmacy.Results:The prevalence of severe ED was 52.4% and that of sarcopenia was 31.6%. At baseline, the prevalence of severe ED was higher in men with sarcopenia than in those without (73.2% vs. 42.8%; adjusted odds ratio [aOR], 1.89; 95% confidence interval [CI], 1.18 to 3.03; p = 0.008). Slow gait speed (aOR, 2.80; 95% CI, 1.18 to 6.62; p = 0.019) and decreased muscle mass (aOR, 2.54; 95% CI, 1.11 to 5.81; p = 0.027) were associated with the incidence of severe ED, while decreased grip strength (aOR, 0.76; 95% CI, 0.30 to 1.91; p = 0.564) was not.Conclusions:Sarcopenia was associated with severe ED. Slow gait speed, and decreased muscle mass was independently associated with incident severe ED at 1 year. Further research is warranted to examine whether an intervention targeting these components can prevent severe ED.
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机译：背景/目的：Sarcopenia和勃起功能障碍（ED）是与老年人的健康状况差和生活质量差的关联。我们调查SARCOPENIA与严重ed的社区住宅年龄较大的男性的关联。根据亚洲工作组共识算法，基于肌肉质量，握力和步态速度。严重的ed被定义为5项国际勃起函数指标调查问卷评分8.洛姆族回归用于研究事故严重的ED和Sarcopenia之间的关联，调整年龄，心血管危险因素，抑郁症和Poly Pharmacy。结果：该严重的患病率为52.4％，SARCOPENIA的患病率为31.6％。在基线时，患有SARCOPENIA的严重ED的患病率高于没有（73.2％与42.8％;调整后的赔率比[AOR]，1.89; 95％置信区间[CI]，1.18至3.03; P = 0.008 ）。步态速度慢速（AOR，2.80; 95％CI，1.18至6.62; p = 0.019）和肌肉质量减少（AOR，2.54; 95％CI，1.11至5.81; p = 0.027）与严重埃德的发生率有关，虽然握力降低（AOR，0.76; 95％CI，0.30至1.91; p = 0.564）.Conclusions：Sarcopenia与严重的ED相关。步态速度缓慢，并且肌肉肿块下降与1年的事故严重相关。有必要进一步研究，以检查针对这些组件的干预是否可以防止严重的ed。
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