Presence and antimicrobial resistance of coagulase-negative staphylococci isolated from animals in ? a Veterinary Teaching Hospital in ? Cyprus

H Sukur; OM Esendal

摘要

Coagulase-negative staphylococci (CoNS) are a group of commensal microorganisms residing on the skin and mucous membranes of both humans and animals. Until recently, they have been regarded as non-pathogenic to livestock and companion animals, but since then, their clinical importance in veterinary medicine has increased with the discovery of their potential pathogenic roles in animals causing skin and soft tissue infections together?with spontaneous abortions and mastitis. Scientific data concerning the presence of CoNS in North Cyprus are very limited. Therefore, the purpose of the study reported herein was to investigate the presence and antimicrobial resistance patterns of CoNS species isolated from various animals presented at the Veterinary Teaching Hospital in North Cyprus between July 2018 and 2019. Staphylococci were isolated from 37.0% (87/235) of the samples submitted, within which 60.9% (53/87) and 39.1% (34/87) were identified as coagulase-positive staphylococci (CoPS) and coagulase-negative staphylococci (CoNS), respectively. Among the CoNS, S.?chromogenes was the most predominantly isolated species (14/34, 41.2%), followed by S.?capitis (5/34, 14.7%) and S.?simulans (4/34, 11.8%). Of these 34?CoNS, 24 (70.6%) and 10 (29.4%) were identified as MRCoNS and MSCoNS, respectively. The CoNS isolates showed relatively high levels of resistance towards amoxicillin/clavulanic acid (19/34, 55.9%), tetracycline (14/34, 41.2%) and penicillin (13/34, 38.2%). In conclusion, the presence of CoNS, especially MRCoNS, and the detection of multiple drug resistant (MDR) species with a high prevalence were regarded as being important since they might limit and have negative effects on the therapeutic treatment options of staphylococcal infections in animals, and might have both public and veterinary concerns.

机译：凝固酶阴性葡萄球菌（CIRS）是一组共数微生物，其居住在人类和动物的皮肤和粘膜上。直到最近，他们被视为牲畜和伴侣动物的非致病性，但从那时，他们在兽医中的临床重要性随着在导致皮肤和软组织感染的潜在的致病作用中发现了它们的潜在致病作用？随着自发的堕胎和乳腺炎。关于北塞浦路斯缺陷的存在的科学数据非常有限。因此，本文报道的研究目的是研究2018年7月至2019年7月北塞浦路斯兽医教学医院的各种动物的存在和抗微生物抗性模式。葡萄球菌分离为37.0％（87/235所提出的样品，在其中确定60.9％（53/87）和39.1％（34/87）分别被鉴定为凝固酶阳性葡萄球菌（COPS）和凝固酶阴性葡萄球菌（CONS）。在缺点中，S.?Chromogenes是最多的孤立物种（14/34,41.2％），其次是S.?capitis（5/34,14.7％）和S.?smulans（4/34,11.8％）。其中34？缺点，24（70.6％）和10（29.4％）分别被鉴定为MRCONS和MSCONS。缺点分离物显示出对阿莫西林/克拉维酸（19/34,55.9％），四环素（14/34,41.2％）和青霉素（13/34,38.2％）的相对高的抗性。总之，缺点的存在，尤其是MRCONs，以及多种患有高患病率的多种耐药物（MDR）物种的含量被认为是重要的，因为它们可能会限制和对动物葡萄球菌感染的治疗方法产生负面影响，并且可能拥有公众和兽医的关注。

Presence and antimicrobial resistance of coagulase-negative staphylococci isolated from animals in ? a Veterinary Teaching Hospital in ? Cyprus

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