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首页> 外文期刊>Journal of Drug Delivery and Therapeutics >An Updated Review on Nanoparticle Based Approach for Nanogel Drug Delivery System
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An Updated Review on Nanoparticle Based Approach for Nanogel Drug Delivery System

机译:基于纳米粒子药物递送系统方法的更新综述

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Nanocomposite hydrogels or nanogels (a nanoparticles composed of a hydrogel) are nanomaterial filled, swollen nanosized networks of deliquescent or amphiphilic compound chains. It may be developed by drug - polymer interactions and to create 3D advanced networks. Nanogel may be ready by many strategies just like the particle gelation, Inverse mini emulsion, Dispersion, Chemical cross linking, fabrication of biopolymers and so on. It can be characterized by SEM, DSC, FTIR, Drug content, Particle size, Zeta potential and drug efficiency. Further, it can be evaluated by in vitro drug release and in vivo study in suitable animal modeling. In this review article, we have focused on basic methodology of nanogels, evaluation terms, their application in industry with future prospects for the researchers.
机译:纳米复合水凝胶或纳米凝胶(由水凝胶组成的纳米颗粒)是纳米材料填充的,肿胀的嗜鼻肿瘤网络或两亲复合链。它可以由药物 - 聚合物相互作用开发并创建3D先进网络。纳尼尔可以通过许多策略准备好,就像粒子凝胶化一样,逆迷你乳液,分散体,化学交叉连接,生物聚合物的制备等。它可以特征在于SEM,DSC,FTIR,药物含量,粒度,Zeta电位和药物效率。此外,可以通过体外药物释放和在适当的动物建模中进行体内研究来评估它。在本综述文章中,我们专注于纳米孔,评估条款,在工业中的应用程序的基本方法,未来研究人员的前景。

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