In pharmaceutical field, many drugs are being invented to combat the existing new diseases. The winds of change in the drug scenario are blowing forcefully worldwide. The emergence of new technologies provides an unique opportunities to exploit novel approaches in drug delivery. A shift from conventional drug delivery to novel drug delivery is noticed as shift from conventional drug delivery suffers from various drawbacks, But these new mighty compounds in drug therapy solely are not sufficient to meet the today’s need. There is an urgent need for the smart technology, as the drugs available suffer from serious problems like poor solubility and poor bioavailability. Most of the drugs that are available therapeutically comes under BCS class II ie, poorly soluble and high lipophilc. To assure progress in drug therapy, the development of new drugs merely is not sufficient. Issues arising in delivery of new drugs should also be addressed. Thus there is an emergent need to improve the bioavailability of these drugs, the only remedy or boon for such drugs is the discovery of some smart technologies which can improve the bioavailability of these drugs. Nano drug delivery systems are the one such universal approach which fulfills the lacuna, which exists in conventional drug delivery systems. These Nano drug delivery systems, improves the pharmacokinetic profiles of many drugs. In 1980 K. Eric Drexler developed and popularized the concept of nanotechnology. In this review a deep insight on Nano structured lipid carriers is discussed elaborating its birth, significant qualities compared to other colloidal systems, its structure, characteristics, preparation and application are spotted.
展开▼
机译：在制药领域，正在发明许多药物以对抗现有的新疾病。药物情景的变化风在全球有力地吹来。新技术的出现提供了一种独特的机会，可以利用药物交付中的新方法。从常规药物递送到新药递送的转变被注意到从常规药物递送的转变产生各种缺点，但这些新的药物治疗中的软化合物完全不足以满足今天的需求。迫切需要智能技术，因为可用的药物遭受严重问题，如贫困性差和生物利用度差。大多数可用治疗的药物都在BCS II类II中，即可溶性和高脂酚。为了确保药物治疗进展，仅仅是新药的发展是不够的。还应解决新药中出现的问题。因此，出现了提高这些药物的生物利用度的必然需要，这种药物的唯一补救措施是对一些可以提高这些药物的生物利用度的一些智能技术的发现。纳米药物递送系统是符合常规药物递送系统中存在的LACUNA的这种通用方法。这些纳米药物递送系统，改善了许多药物的药代动力学谱。 1980年K. Eric Drexler开发并推广了纳米技术的概念。在本篇综述中，讨论了对纳米结构脂质载体的深层洞察，讨论了与其他胶体系统相比的出生，显着的品质，其结构，特征，制备和应用。
展开▼
