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外文期刊>Journal of Ovarian Research
>Application of receiver operating characteristic curve in the assessment of the value of body mass index, waist circumference and percentage of body fat in the Diagnosis of Polycystic Ovary Syndrome in childbearing women
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Application of receiver operating characteristic curve in the assessment of the value of body mass index, waist circumference and percentage of body fat in the Diagnosis of Polycystic Ovary Syndrome in childbearing women
Background There are various parameters?to analyze obesity, however, no standard reference to predict, screen or diagnose PCOS with various obesity parameters has been established, and the accuracy of these parameters still needs to be studied.This study was to?use the receiver operating characteristic (ROC) curve to explore the different values of three obesity parameters, body mass index (BMI), waist circumference (WC) and percentage of body fat (PBF) in the diagnosis of polycystic ovary syndrome (PCOS) in Chinese childbearing women. Methods Three hundred patients who were diagnosed with PCOS at Center of Reproductive Medicine and Genetics of Peking University First Hospital were enrolled in this study, and 110 healthy age-matched women were enrolled as controls. The characteristics of BMI, WC and PBF in PCOS patients were analyzed. Results Compared with the control group, all the three obesity parameters were significantly increased in PCOS group. In terms of ROC area under the curve, WC??PBF??BMI, and they were all significantly different from those of the control. At a cut-off point of 80.5?cm, WC has a sensitivity of 73.6?% and a specificity of 85?% in diagnosis of PCOS; At a cut-off point of 29?%, PBF has a sensitivity of 88.2?% and a specificity of 57.7?% in diagnosis of PCOS; and at a cut-off point of 26.6?kg/msup2/sup, BMI has a sensitivity of 54.5?% and a specificity of 98?% in diagnosis of PCOS. Conclusion WC, BMI and PBF are valuable in screening and diagnosis of PCOS in Chinese childbearing women. PBF can be used to screen PCOS as it has a better sensitivity, while BMI can be used in the diagnosis of PCOS as it has a better specificity.
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机译：背景技术有各种参数？为了分析肥胖症，然而，没有建立具有各种肥胖参数的预测，屏幕或诊断PCO的标准参考，并且需要研究这些参数的准确性。这项研究是？使用接收器经营特征（ROC）曲线，用于探讨三种肥胖参数，体重指数（BMI），腰围（BMI），腰围（PBF）的百分比（PBF）的不同值，在中国生育女性中的多囊卵巢综合征（PCOS）的诊断中。方法采用北京大学第一医院生殖医学中心诊断患有PCOS的三百款患者，均注册了110名健康年龄匹配的妇女作为控制。分析了PCOS患者BMI，WC和PBF的特征。结果与对照组相比，PCOS组中所有三种肥胖参数明显增加。就曲线下的ROC区域而言，WC？> PBF？>？BMI，它们与控制器的显着不同。在80.5Ω·厘米的截止点，WC的敏感性为73.6？％，并且在PCOS的诊断中的85倍的特异性为85？％;在29℃的截止点，PBF的敏感性为88.2〜％，特异性为PCOS的诊断情况下为57.7？％;并且在截止点为26.6Ω·kg / m 2 ，BMI的敏感性为54.5‰的敏感性，并且在PCOS的诊断中具有98Ω％的特异性。结论WC，BMI和PBF在中国生育女性PCOS的筛查和诊断中有价值。 PBF可用于筛选PCOS，因为它具有更好的灵敏度，而BMI可以用于PCOS的诊断，因为它具有更好的特异性。
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