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首页> 外文期刊>Journal of Sport and Health Science >Handgrip strength and health outcomes: Umbrella review of systematic reviews with meta-analyses of observational studies
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Handgrip strength and health outcomes: Umbrella review of systematic reviews with meta-analyses of observational studies

机译:Handgrap强度和健康结果:伞形审查荟萃分析的系统性评论

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PurposeThe aim of the present study was to assess both the credibility and strength of evidence arising from systematic reviews with meta-analyses of observational studies on handgrip strength and health outcomes.MethodsAn umbrella review of systematic reviews with meta-analyses of observational studies was conducted. We assessed meta-analyses of observational studies based on random-effect summary effect sizes and theirpvalues, 95% prediction intervals, heterogeneity, small-study effects, and excess significance. We graded the evidence from convincing (Class I) to weak (Class IV).ResultsFrom 504 articles returned in a search of the literature, 8 systematic reviews were included in our review, with a total of 11 outcomes. Overall, nine of the 11 of the outcomes reported nominally significant summary results (p< 0.05), with 4 associations surviving the application of the more stringentpvalue (p?
机译:目前研究的目的是评估系统审查的可信度和力量,并对手柄强度和健康成果的观察研究中的观察研究进行了系统评价。关于对观察研究的荟萃分析的系统性评论的审查审查。我们评估了基于随机效应摘要效应大小和体育率,95%预测间隔,异质性,小型研究效果和过度意义的观测研究的荟萃分析。我们将证据评为令人信服(I级)到弱势(四年级)。从504篇文章中返回的文章返回,8个系统评价包括在我们的评论中,共有11个结果。总体而言,11个结果中的九个报告了名义上重大的概要结果(P <0.05),4名关联在申请更严格的比例(P?<10?6)。没有结果令人信服的证据。三个关联显示II类证据(即高度暗示):(1)基线的较高的手柄价值与一般人群的死亡风险小调有关(n?= 34研究;样本大小?=?1,855,817;相对风险= 0.72,95%置信区间(95%CI):0.67-0.78),(2)混合群体的心血管死亡风险(n?= 15次;相对风险?= 0.84,95%CI:0.78-0.91 )和(3)残疾发生率(n?= 7研究;相对风险?= 0.76,95%CI:0.66-0.87)。结论目前的结果表明,手工强度是一般健康状况的有用指标用于早期全因和心血管死亡率,以及残疾。为了进一步了解干预策略,现在需要将来的研究完全理解将手柄强度分数与这些健康结果联系起来的机制。

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