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外文期刊>Journal of the Indian Medical Association.
>Prevalence, Demographics and risk factors of Intracranial stenosis in Ischemic Stroke Patients admitted at a teaching government hospital in Central Gujarat
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Prevalence, Demographics and risk factors of Intracranial stenosis in Ischemic Stroke Patients admitted at a teaching government hospital in Central Gujarat
Introduction : Ischemic Strokes (IS) occur when an artery of brain is occluded by thrombosis orembolus.It can be caused either by large artery atherosclerosis, cardioembolic source, small vesseldisease and in some rare cases such as hypercoagulable state or in few cause can’t be determined(cryptogenic stroke). We chose to compare Intracranial Arterial Stenosis (ICAS) IS with non-ICAS ISpatients to determine whether particular risk factors,demographics or clinical characteristics wereparticularly associated with ICAS.Material and Method : We collected data of 153 stroke patients admitted at GMERS General Hospital,Gotri, Vadodara for three months from March 2018-May 2018.Out of which 50 IS patients passed ourinclusion criteria. Their history, laboratory values and imaging. MRA and CTA imaging results wereassessed and recorded. Statistics was carried out using Excel, MedCalc and Graph Pad Prism.Results : In our study, out of 73 Stroke patients, 21 (29%) were diagnosed as stenotic and classifiedas ICAS. The remaining IS were classified as Non-ICAS. Among the IS patients (N=50), ICAS accountedfor 21 (42%); females had a dramatically lower Time since onset (TSO) than males, with few arrivingwithin one hour. Majority (71.4%) of the males iarrived after 24 hours while half (53%) of the femalesarrived after 24 hours to the hospital. The TSO was longest in rural lower-middle class patients (mean20 days). On comparison of age,median age was higher in ICAS than non-ICAS patients.High neutrophilcount was found both in ICAS as well as Non-ICAS groups and neutrophil to lymphocyte ratio (NLR) wasdifferent between both the groups.Tobacco and Alcohol abuse, Diabetes Mellitus were major riskfactors.Cardiac disorder were seen in very few patients whereas Past Stroke event had occurred inseveral of the IS patients, with no significant differences observed in the two groups (ICAS and nonICAS)studied.Conclusion : Demographics, risk factors and laboratory values were obtained from all the patients.Higher proportion of males was observed in all IS patients, Lower-middle class patients had the longestTSO. There was no significant difference in risk factors. Significant difference in neutrophilia wasstriking and showed strong inverse relationship to lymphocytes in ICAS IS patients and moderateinverse relationship in non-ICAS IS patients.
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机译：介绍：缺血性卒中（是）在血栓形成的血栓肿瘤堵塞时发生，可以通过大动脉动脉粥样硬化，心脏病源，小容器，以及在一些罕见的病例（如超哥状态）中引起的确定（隐生脑卒中）。我们选择比较颅内动脉狭窄（ICAS）是用非ICAS等体进行比较，以确定是否具有与ICAS的特殊危险因素，人口统计学或临床特征。材料和方法：我们收集了153名卒中患者在Gotri综合医院承认的数据，Vadodara从2018年3月至2018年5月至2018年5月。其中50名是患者通过了OURINCLUSION标准。他们的历史，实验室价值观和成像。 MRA和CTA成像结果不驱动和记录。统计数据是使用Excel，Medcalc和Graph Pad Prism进行的。结果：在我们的研究中，在73名中风患者中，21例（29％）被诊断为狭窄和分类索斯。剩下的被归类为非ICA。在患者（n = 50）中，ICAS占21条（42％）;女性在发病（TSO）之后的较低时间大幅下降，很少一小时。大多数（71.4％）的男性在24小时后IARIVED，而24小时后的女性攻击的一半（53％）到医院。 TSO在农村下层患者中最长（平均20天）。与年龄相比，ICA中位年龄高于非ICAS患者。在ICAS和非ICAS组中发现了高中性粒组，并且在群体之间存在淋巴细胞比（NLR）。糖尿病是主要的冒险因素。在很少有患者中看到了心脏病，而过脑卒中事件已经发生了患者，在两组（ICAS和NONICAS）中没有观察到的显着差异。结论：人口统计，危险因素和实验室从所有患者中获得的价值。在所有患者中观察到的男性比例，中下患者都有长期的患者。风险因素没有显着差异。中性粒细胞增多差异差异，表现出与ICAS中的淋巴细胞的强逆关系是患者，非ICAS中的分析关系是患者。
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