Drug Resistance Spread in 6 Metropolitan Regions, Germany, 2001–20181

Melanie Stecher; Antoine Chaillon; Christoph Stephan; Elena Knops; Niko Kohmer; Clara Lehmann; Josef Eberle; Johannes Bogner; Christoph D. Spinner; Anna Maria Eis-Hübinger; Jan-Christian Wasmuth; Guido Sch?fer; Georg Behrens; Sanjay R. Mehta; J?rg Janne Vehreschild; Martin Hoenigl

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Drug Resistance Spread in 6 Metropolitan Regions, Germany, 2001–20181

机译：耐药在德国601-20181中的6个大都会地区扩展

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We analyzed 1,397 HIV-1 pol sequences of antiretroviral therapy-naive patients in a total of 7 university hospitals in Bonn, Cologne, Frankfurt, Hamburg, Hannover, and Munich, Germany. Phylogenetic and network analysis elucidated numerous cases of shared drug resistance mutations among genetically linked patients; K103N was the most frequently shared mutation.

机译：我们分析了抗逆转录病毒治疗 - 幼稚患者的1,397名HIV-1 POL序列，共7名大学医院在波恩，科隆，法兰克福，汉堡，汉诺威和慕尼黑，德国。系统发育和网络分析阐明了遗传链接患者的许多共用药物抗性突变病例; K103N是最常见的共享突变。

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《Emerging Infectious Diseases》 |2020年第10期|共5页
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Melanie Stecher; Antoine Chaillon; Christoph Stephan; Elena Knops; Niko Kohmer; Clara Lehmann; Josef Eberle; Johannes Bogner; Christoph D. Spinner; Anna Maria Eis-Hübinger; Jan-Christian Wasmuth; Guido Sch?fer; Georg Behrens; Sanjay R. Mehta; J?rg Janne Vehreschild; Martin Hoenigl;
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中图分类传染病;
关键词
ARTGermanyHIV transmissionantimicrobial resistanceantiretroviral therapymutationsphylogenetic analysispublic health;

机译：Artgermanyhiv抗病性抵抗性抗抵抗力病毒病毒治疗乳髓发育分析公共健康;

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1. Laboratory surveillance of antimicrobial resistance and multidrug resistance among Streptococcus pneumoniae isolated in the Kinki region of Japan, 2001-2015 -Comparison of the prevalence of drug-resistant strains before and after introduction of conjugated pneumococcal vaccined- [J] . Hirofumi Toda, Kaori Satoh, Masaru Komatsu, Journal of infection and chemotherapy: official journal of the Japan Society of Chemotherapy . 2018,第3a4期

机译：日本Kinki地区中肺炎链球菌患者抗菌药物抗菌性和多药耐药性的实验室监测 - 缀合肺炎疫苗疫苗前后耐药菌株患病率的普通术 -
2. Dramatic increase of third-generation cephalosporin-resistant E. coli in German intensive care units: secular trends in antibiotic drug use and bacterial resistance, 2001 to 2008 [J] . Elisabeth Meyer, Frank Schwab, Barbara Schroeren-Boersch, Critical care : . 2010,第3期

机译：在德国重症监护病房中，第三代头孢菌素耐药性大幅度增加：2001年至2008年抗生素使用和细菌耐药性的长期趋势
3. Epidemiology of primary drug resistance in chronically HIV-infected patients in Nordrhein-Westfalen, Germany, 2001-2005 [J] . Oette M, Kaiser R, Daumer M, DMW: Deutsche Medizinische Wochenschrift . 2007,第18期

机译：2001-2005年德国北莱茵-威斯特法伦州的慢性HIV感染患者的原发耐药性流行病学
4. Emergence of suburban employment centres in German metropolitan regions: Impacts on commuter traffic, 1987-2007 [C] . Dennis Guth International Conference on Urban Planning, Regional Development and Information Society . 2010

机译：德国大都市区郊区就业中心的出现：1987 - 2007年对通勤交通的影响
5. The spread of drug resistance in gram negative bacteria. [D] . Berman, Hillary Fanya. 2013

机译：耐药菌在革兰氏阴性细菌中的传播。
6. Drug Resistance Spread in 6 Metropolitan Regions Germany 2001–2018 [O] . Melanie Stecher, Antoine Chaillon, Christoph Stephan, 2020

机译：涉及德国601-2018的6个大都市地区的耐药率
7. 1280. Geospatial Spread of HIV in the Cologne-Bonn Region, Germany: From 2001 to 2016 [O] . Melanie Stecher, Martin Hoenigl, Anna-Maria Eis-Huebinger, 2018

机译：1280.艾滋病毒在德国科隆 - 波恩地区的地理空间传播：从2001年到2016年

Drug Resistance Spread in 6 Metropolitan Regions, Germany, 2001–20181

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