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首页> 外文期刊>Egyptian Journal of Anaesthesia >Case report: successful prophylactic use of intravenous lipid emulsion to prevent local anesthetic systemic toxicity after inadvert intravenous administration of bupivacaine
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Case report: successful prophylactic use of intravenous lipid emulsion to prevent local anesthetic systemic toxicity after inadvert intravenous administration of bupivacaine

机译:案例报告:成功的预防性使用静脉内脂质乳液,以防止局部麻醉系统毒性在静脉内施用Bupivacain后

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Bupivacaine is a local anesthetic drug that carries catastrophic adverse effects. On exceeding the toxic dose significant cardiotoxic and neurotoxic consequences emerge. The maximal toxic dose of Bupivacaine for local applications is 2 mg.kg-1. The exact hazardous dose for intravenous administration is unknown. Abdominal hysterectomy was scheduled for our 57-year-old patient. She received 20 mg of Bupivacaine intravenously by accident and showed no evidence of cardiac or neurological toxicity. The explanation for this is unknown, although it could be owing to the very low dose, which was less than the toxic amount, or to our patient’s early lipid emulsion prophylaxis.
机译:Bupivacaine是一种携带灾难性不利影响的局部麻醉药。 超过毒性剂量显着的心脏毒性和神经毒性后果出现。 用于局部应用的最大毒性剂量为2mg.kg-1。 静脉内给药的确切危险剂量未知。 腹部子宫切除术计划为我们的57岁患者。 她常时收到20毫克Bupivacaine,没有表现出心脏或神经系统毒性的证据。 对此的解释是未知的,尽管它可能是由于低剂量,其小于毒性量,或者我们的患者早期的脂质乳液预防。

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