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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Sexual Maturity in Adolescents Suffering from Sickle Cell Disease: A Cross-sectional Study
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Sexual Maturity in Adolescents Suffering from Sickle Cell Disease: A Cross-sectional Study

机译:患有镰状细胞病的青少年的性成熟:横断面研究

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Sickle Cell Disease (SCD) is an inherited chronic haemolytic anaemia.The diseased person suffers from various complications such as anaemia, frequent infection, fever, handfoot syndrome, stroke, etc.Puberty changes includes the appearance of the secondary sexual characteristics, increase in height, change in body composition and development of reproductive capacity.Aim: To study the sexual maturity and effect of multiple blood transfusions in adolescents suffering from SCD.Materials and Methods: It was a cross-sectional study conducted on 35 adolescents of age group 11 to 15 years, suffering from SCD.Study was conducted over a period of six months from March 2018 to September 2018 at Department of Paediatrics.SCD was diagnosed by Haemoglobin (Hb) electrophoresis.Weight and height were measured of all the participants.For assessing the sexual maturity, Tanners staging was used.Unpaired t-test was done for data analysis.Results: The mean age of the patients was 13.03±1.7 years.There were 25 males and 10 females.The mean age of male patients between Tanner stage 2(14.63±0.52 years) and Tanner stage 3 (14.75±0.5 years) was significantly higher than the Indian data for males (11.3 and 12.8 years, respectively).The mean age of female patients between Tanner stages 2 (13.5±2.12 years) and Tanner stage 3 (14.33±1.16 years) was higher than the Indian reference data for girls (10.2 and 11.6 years respectively).Conclusion: This study concluded that adolescents with SCD were significantly shorter in height and weight than the standard reference population.Sexual maturity is delayed in adolescents with sickle cell anaemia.
机译:镰状细胞疾病(SCD)是一种遗传的慢性溶血性Anaemia。患病者患有各种并发症,如贫血,频繁感染,发热,手枪综合征,中风等.Pubry变化包括外观的外观,高度增加,身体成分的变化和生殖能力的发展。论患有SCD的青少年的性成熟和多发性血液输血的效果:它是在35岁的年龄组中进行的横断面研究。 15年来,患有SCD.STUDY于2018年3月至2018年9月在2018年3月至2018年9月进行的,在儿科管局诊断出血红蛋白(HB)电泳诊断。重量和高度是针对所有参与者衡量的。为评估使用性成熟,使用了横幅分段。对于数据分析来说是为数据分析完成的。结果:患者的平均年龄为13.03±1.7岁。 25名男性和10名女性。坦纳阶段2(14.63±0.52年)和Tanner第3阶段(14.75±0.5岁)之间的男性患者的平均年龄明显高于印度数据(分别为11.3和12.8岁)。坦纳阶段2(13.5±2.12年)和Tanner第3阶段(14.33±1.16岁)的平均年龄高于女孩的印度参考数据(分别为10.2和11.6岁)。结论:这项研究得出结论,青少年对于高度和体重而不是标准参考人群的高度和体重显着较短。患有镰状细胞贫血的青少年延迟了成熟度。

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