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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Anti-Inflammatory Activity of Oxycarotenoid Extracts Isolated from Coriander Leaves (Coriandrum Sativum) and Curry Leaves (Murraya koenigii) on Carrageenan Induced Acute Inflammation in Rats
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Anti-Inflammatory Activity of Oxycarotenoid Extracts Isolated from Coriander Leaves (Coriandrum Sativum) and Curry Leaves (Murraya koenigii) on Carrageenan Induced Acute Inflammation in Rats

机译：从香菜叶（Coriandrum sativum）和咖喱叶（Murraya Koenigii）抗炎活性的含氧蛋白提取物（Coriandrum）和咖喱叶（Murraya Koenigii）诱导大鼠急性炎症

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Green leafy vegetables are important sources of polyphenols and carotenoids which possess both antioxidant and anti-inflammatory activities.Aim: To study the anti-inflammatory activity of oxycarotenoid extracts isolated from coriander leaves (Coriandrumsativum) and curry leaves (Murraya koenigii) in carrageenan induced acute paw oedema in rats.Materials and Methods: Oxycarotenoid extracts were isolated from the coriander leaves (Coriandrum sativum) and curry leaves (Murraya koenigii) and they were assessed for antiinflammatory activities by in-vivo methods.The in-vivo antiinflammatory activity was evaluated in carrageenan induced acute paw oedema model.Indomethacin at a dose of 20 mg/Kg body weight was used as standard anti-inflammatory drug.Results: The results revealed that oxycarotenoids extracted from coriander leaves administered at a dose of 40 mg/ kg body weight showed an inhibition of 53.33% whereas the oxycarotenoids extracted from curry leaves showed an inhibition of 60% at the sixth hour after carrageenan injection.The results are comparable with those of indomethacin (20 mg/ Kg body weight) administered group which showed an inhibition of 55.53% Conclusion: These findings suggest that oxycarotenoid extracts isolated from leafy vegetables (coriander leaves and curry leaves) have significant anti-inflammatory activities.
机译：绿叶蔬菜是多酚和类胡萝卜素的重要来源，其具有抗氧化和抗炎活动。为了研究从香菜叶（Coriandrumsativum）和咖喱叶（Coriandrumsativum）和Currya叶（Murraya Koenigii）诱导急性胃癌（Coriandrumsativum）的胃癌提取物的抗炎活动爪子水肿在大鼠中。材料和方法：含氧菌蛋白提取物与香菜叶（Coriandrum sativum）和咖喱叶（Murraya Koenigii）分离，并通过体内方法评估抗炎活性。评估体内抗炎活性。在评估in-Vivo抗炎活动角叉菜胶诱导急性爪水肿模型。用剂量为20mg / kg体重的吲哚美辛被用作标准的抗炎药物。结果显示，从40mg / kg体重的剂量施用的香菜叶中提取的含氧纤维素。抑制53.33％，而从咖喱叶中提取的含氧单向蛋白在t处显示出60％的抑制训他的角叉菜单注射后第六个小时。结果与吲哚美辛（20mg / kg体重）给药组的抑制作用，其抑制了55.53％：这些研究结果表明，从绿叶蔬菜中分离的氧遗传蛋白提取物（香菜叶和咖喱叶）具有显着的抗炎活动。

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