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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Retrospective Audit of Phacomorphic Glaucoma in Last 12 Years in a Tertiary Eye Care Centre, New Delhi, India
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Retrospective Audit of Phacomorphic Glaucoma in Last 12 Years in a Tertiary Eye Care Centre, New Delhi, India

机译：在印度新德里的第三次眼科中心，在过去12年中对Phacomorphic青光眼的回顾性审计

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Phacomorphic glaucoma is a type of secondary glaucoma caused by lens swelling in eyes with mature or intumescent cataract.It is encountered more commonly in developing countries.Its management includes initial lowering of Intraocular Pressure (IOP) followed by definitive treatment of removal of lens by cataract surgeries.The visual prognosis remains unpredictable due to the irreversible optic nerve damage that may have incurred in a matter of few days.It is equally pertinent to know the postoperative IOP values and whether these patients would require long term Anti-Glaucoma Medications (AGM).The role of Laser Peripheral Iridotomy (LPI) in IOP control preoperatively in such patients also needs to be evaluated.Aim: To assess the visual outcome, IOP control and the requirement of AGM after cataract surgery in phacomorphic glaucoma.Materials and Methods: This was a retrospective, observational study conducted from March 2019 to January 2020 on all patients diagnosed with phacomorphic glaucoma at the tertiary eye care centre.The primary variables were IOP and visual acuity.All patients underwent a complete ophthalmic examination.Cataract surgery was done after instituting treatment for IOP control.Preoperative LPI was done according to consulting doctors’ discretion.Trabeculectomy was combined with cataract surgery based on surgeons’ decision.Patients were followed for 6 weeks postoperatively.Fisher-test and paired t-test were used for statistical analysis.Results: A total of 118 patients (25 males and 93 females, mean age 64.55±6.35 years) were recruited in the study and 94 patients followed-up till last visit at 6 weeks.The mean presenting IOP was 39.55±12.55 mmHg.The mean IOP at day-1 postoperatively was 14.66±4.55 mmHg, the difference was statistically significant (p-value <0.001).There was a significant drop in IOP seen postoperatively at day 1 and 6 weeks (p<0.001).At 6 weeks, the mean IOP was 13.19±3.83 mm Hg.A combined cataract extraction and trabeculectomy did not result in statistically significant difference in the final IOP values.At 6 weeks follow-up, 87.23% patients did not require any AGMs; 63.83% patients gained good vision, 26.59% gained borderline vision and 9.58% had poor vision.LPI resulted in a better IOP control preoperatively (p=0.003).Conclusion: Cataract surgery alone results in good IOP control in phacomorphic glaucoma without a need for long term AGMs.However, to prevent permanent angle damage and disc changes an early surgical intervention is required.LPI appears to have a beneficial role in controlling the preoperative IOP in these eyes.
机译：phacomorphic glaucoma是一种由镜片肿胀引起的眼睛肿胀，成熟或膨胀性白炽性。在发展中国家中更常见。管理包括初始降低眼压（IOP），然后通过白内障去除镜片手术。目视预后仍然是不可预测的，因为可能在几天内可能产生的不可逆转的视神经损伤。同样有关了解术后IOP值以及这些患者是否需要长期抗青光眼药物（AGM） 。激光外周虹膜膜（LPI）在此类患者中的IOP对照中的作用也需要进行评估。术语：评估白内障手术中的视觉结果，IOP控制和AGM的需求。是从2019年3月到1月2020年3月进行的回顾性，观察研究，所有患者均诊断出顽皮素glau昏迷在三级眼科护理中心。主要变量是IOP和视力。所有患者接受了完整的眼科检查。在为IOP Control治疗的治疗后进行了完整的眼科检查。根据咨询医生自行决定进行了术后LPI完成。结合了术语基于外科医生的决策的白内障手术。术后6周患者患者。测试和配对T检验用于统计分析。结果：共有118名患者（25名男性和93名女性，平均64.55±6.35岁月招募在该研究中，94名患者随访，直到最后一次访问，直到最后一次访问。IOP的平均值为39.55±12.55 mmHg。术后第1天的平均IOP为14.66±4.55mmHg，差异有统计学意义（ p值<0.001）。在第1天和第6周（P <0.001）时，在术后术后的IOP是一个显着的下降（P <0.001）.AT 6周，平均IOP为13.19±3.83mm HG.A组合白内障提取和TRABECULECECTOMY不会导致最终IOP值的统计学显着差异。6周随访6周，87.23％的患者不需要任何AGM; 63.83％的患者获得了良好的视觉，获得了26.59％的边缘视觉和9.58％的Vision.LPI术前导致IOP控制更好（P = 0.003）。结论：单独的手术在不需要的情况下，单独导致良好的IOP对照控制良好的IOP对照无需然而，为了防止永久角度损伤和圆盘改变，需要早期手术干预.LPI似乎在控制这些眼中的术前IOP方面具有有益的作用。

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