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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Evaluation of Ropivacaine versus Ropivacaine with Fentanyl for Postoperative Epidural Analgesia in Patients Undergoing Elective Lower Abdominal Oncosurgeries- A Randomised Clinical Study
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Evaluation of Ropivacaine versus Ropivacaine with Fentanyl for Postoperative Epidural Analgesia in Patients Undergoing Elective Lower Abdominal Oncosurgeries- A Randomised Clinical Study

机译：Ropivacaine与芳炔基的术后硬膜外镇痛与冬季腹膜胸腺镇痛的评价 - 随机临床研究

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Epidural analgesia has emerged as one of the preferred and convenient modes of intraoperative and postoperative management owing to advantage of not interfering with metabolic functions, better tolerability and decrease in reflex activity, similar analgesic properties, less motor blockade and decreased propensity of cardiotoxicity.Neuraxial opioids like fentanyl used in epidural analgesia offer advantage of augmenting local anaesthetic effect and reducing the anaesthetic and analgesic requirement.Aim: To compare the adequacy of analgesia, requirement of rescue analgesics between 0.2% ropivacaine and 0.2% ropivacaine with 2 mcg/cc fentanyl.Materials and Methods: The randomised clinical study was carried out from September 2016 to May 2018 in 70 patients (35 in each group) of American Society of Anaesthesiologists (ASA) 1 and 2 scheduled for elective lower abdominal oncological surgeries.The anaesthetic intervention in group R was 0.2 % ropivacaine and group RF was 0.2% ropivacaine with 2 mcg/cc fentanyl.All data was statistically analyzed and compared using Student t-test, Chi-square/Fisher-Exact test.The p-value <0.05 was considered to be significant.Results: Both the groups were compatible with regard to demographic data and haemodynamic variables.The mean Visual Analogue Scale (VAS) were higher in group R compared to group RF at 0, 2, 4, 12, 18 and 24 hours but the observed difference in both the groups was not statistically significant except at 1 and 6 hours.Number of rescue analgesics as epidural boluses (p-value=0.007) and paracetamol (p-value=0.022) requirement were more in group R compared to group RF respectively.Conclusion: On account of adequate postoperative analgesia, haemodynamic stability, ropivacaine with fentanyl is a better option than ropivacaine alone for epidural infusion.
机译：硬膜外镇痛作为术中和术后管理的优选和方便模式之一，由于不干扰代谢功能，更好的可耐受性和反射活动的降低，类似的镇痛性，较少的电机阻滞和降低的心脏毒性.NEURAXIAL APIOID与硬膜外镇痛中使用的芬太尼提供了增强局部麻醉效果的优势，并减少麻醉和镇痛要求。为了比较镇痛的充足性，恢复镇痛药的需求0.2％Ropivacaine和0.2％Ropivacaine的抢救镇痛药与2mcg / cc Fentanyl.materials。方法：随机临床研究于2016年9月至2018年于2018年5月，在美国麻醉学家（ASA）1和2中的70名患者（每组35名患者中进行，该学会1和2调度适用于选择性的下腹部肿瘤肿瘤肿瘤肿瘤肿瘤是0.2％Ropivacaine和Grous RF为0.2％Ropivacaine 2 MCG / CC Fentanyl.all数据在统计分析并使用学生T检验进行比较，Chi-Square / Fisher-Excreation Test.P值<0.05被认为是显着的。结果：两组都与之兼容人口统计数据和血管动力学变量。r组r相比，与0,2,4,12,18和24小时的组r次较高，但除了左右，两组的观察到的差异在统计学上没有统计学意义1和6小时。分别与组RF分别相比，rescue镇痛药（p值= 0.007）和扑热息痛（p值= 0.022）的要求更多。结论：由于术后镇痛充足，血液动力学稳定性，罗比卡因与芬太尼是比单独的硬膜外输液的罗哌卡因更好的选择。

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