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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Postoperative Hypoparathyroidism: Presentation, Clinical Features and Long-term Follow-up from Tertiary Care Hospital
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Postoperative Hypoparathyroidism: Presentation, Clinical Features and Long-term Follow-up from Tertiary Care Hospital

机译：术后患有患有过的疗效：介绍，临床特征和高等教育医院的长期随访

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Hypoparathyroidism is commonly seen after total thyroidectomy.Though most of the time it is transient in nature but permanent decrease in function of the parathyroid function is also possible.Aim: A retrospective analysis of clinical presentation, treatment, prevalence of complications of hypoparathyroidism and its treatment with active vitamin D analogues was conducted.Materials and Methods: A retrospective cohort study followed by location and duration of study of all patients who developed Permanent Hypoparathyroidism (PH) and who were regular in follow-up for at least three years.Any patient with intact Parathyroid Hormone (iPTH) levels<13 pg/mL and was on replacement therapy with calcium and/ or vitamin D for at least one year after surgery is labelled as PH.Data of their treatment, serum calcium, phosphorous, creatinine, urine calcium/creatinine ratio and renal ultrasound was recorded.Data was represented as percentage, mean and standard deviation.Statistical analysis was conducted using SPSS version 19.Results: Out of the 23 patients enrolled, three were male and 20 were female with a mean age of 41.2±15.2 years.The mean duration of follow-up was 48±28 months.Clinical complications in 12 patients were observed.Two patients developed renal colic due to renal stone on follow-up.None of the patients developed renal failure.Conclusion: PH causes considerable morbidity and economic burden to family due to its lifelong treatment and monitoring.It requires regular follow-up and monitoring to prevent complications of disease as well as its treatment with active calcium salts.Around 50% of the patients suffered few relevant clinical events requiring hospitalisation.
机译：总甲状腺切除术后，常见的甲状腺内切除术后常见。虽然大部分时间都是瞬态的，但甲状旁腺功能的功能永久性降低也是可能的。临床介绍，治疗，低丙酮功能亢进的并发症患病率的回顾性分析及治疗进行活性维生素D类似物的方法。材料和方法：一种回顾性队列研究，然后进行研究的位置和持续时间，所有患者开发了永久性低丙酮毒性（pH），谁定期在后续行动中至少有三年。完整的甲状旁腺激素（iPth）水平<13 pg / ml，并且在手术后至少一年的钙和/或维生素D进行替代疗法，标记为其治疗，血清钙，磷，肌酐，尿液钙的pH.data /肌酐比率和肾超声被记录.DATA表示为百分比，平均值和标准偏差。统计分析是进行的使用SPSS版本19.Results：从注册的23名患者中，三个是男性，20名女性，平均年龄为41.2±15.2岁。后续的平均持续时间为48±28个月。12名患者的临床并发症被观察到。患者由于肾脏石头而出现了肾结构。患者的肾功能衰竭。结论：由于其终身治疗和监测，pH值导致家庭发病率和经济负担。它需要定期随访并监测以防止疾病并发症以及其活性钙盐的治疗。患者的50％患者遭受了需要住院治疗的有关临床活动。

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