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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Persistence of Symptoms after Acute COVID-19 Infection- An Experience from a Tertiary Care Centre in South India
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Persistence of Symptoms after Acute COVID-19 Infection- An Experience from a Tertiary Care Centre in South India

机译：急性Covid-19感染后症状持续存在 - 印度南部三级护理中心的经验

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COVID-19 pandemic is posing a challenge not only with sheer number of people infected but also with the large number of patients with persistent symptoms of COVID19 infection.A proper understanding of the magnitude and associated factors of persistent COVID-19 symptoms will go a long way in planning treatment and control strategies.Aim: To determine the proportion of patients who have persistent symptoms post-acute COVID-19 infection and to determine the factors associated with it, among those who have been discharged from Government Medical College, Thrissur.Materials and Methods: The current cross-sectional study was conducted among 335 patients who were admitted and discharged with COVID-19 infection in Government Medical College, Thrissur, Kerala, a tertiary care institution in southern India between December 2020 and February 2021.They were contacted through a telephonic interview 28 days from symptom onset through a semi-structured interview schedule.The questions included basic demographic details, symptomatology at admission, persistent symptoms at 28 days after onset and other clinical details including comorbidities.For defining postCOVID-19 symptom persistence National Institute for Health and Care (NICE) guidelines were used.Association between persistent symptoms and selected factors was done by Chisquare test.Results: Out of the 335 patients, the persistence of symptoms of COVID-19 infection after 28days of symptom onset was 221 (66%) C.I -60.7-70.8%).Persistence of two or more COVID-19 symptoms after 28 days of onset was seen in 120 (35.8%).The most common persistent symptoms among the patients were fatigue in 109 (32.5%) of people followed by dyspnoea in 77 (23%), cough in 45 (13.4%) and myalgia in 37 (11%) patients Highest persistence was seen in Category C patients where symptoms were persisting in 75%.Persistence was also higher in those with diabetes mellitus, those who received oxygen support and those who were in Intensive Care Unit (ICU) or ventilator and the association was statistically significant(p-value<0.05).Conclusion: The study shows that 2/3rd of patients still continues to have persistent symptoms even after 28 days of symptom onset.Health systems should be prepared to face the consequences of morbidities caused by post COVID-19 syndrome.
机译：COVID19流行病冒充不仅与人感染数量之多，而且还与大量的患者的幅度COVID19 infection.A正确的认识持续症状和持续COVID19症状相关因素的挑战还有很长的方式规划治疗和控制strategies.Aim：要确定谁拥有持续的症状患者的比例急性期后COVID-19感染，并确定与之相关联的，其中那些谁已经从政府医学院排出的因素，Thrissur.Materials方法：目前的横断面研究在人群当中谁被接纳，并与COVID-19感染在政府医学院，特里苏尔，喀拉拉邦，在印度南部的一个三级医疗机构2020年12月和二月2021.They之间的放电进行了联系，335例患者进行通过电话采访，从症状出现28天通过半结构访谈schedule.The问题包括基本人口统计信息，症状入院，28天持续症状发病后和其他临床资料，包括comorbidities.For定义postCOVID-19症状持续国立卫生研究院和保健（NICE）的指导方针是持续的症状和选择因素之间used.Association做通过卡方检验。结果：在对335名患者中，的COVID-19感染的症状出现症状为221（66％）的后28天持久CI -60.7-70.8％）的两个或更多个COVID-19症状的持续后发病后28天内在120（35.8％）被看见。之中的患者中最常见持久的症状是在109（32.5％）疲劳的人随后呼吸困难在77（23％），咳嗽在45（13.4％）和肌痛在37（11％）患者最高持续见于C类患者，其中症状在75％.Persistence是那些有糖尿病也较高坚持，那些谁收到的氧气支持和那些谁是在重症监护室（ICU）或已经ntilator和关联有统计学显著（p值<0.05）。结论：该研究表明，患者2 /第三仍继续有持续性症状甚至后症状onset.Health 28天系统应准备面对的后果造成后COVID-19综合征发病率。

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