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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Predictive Value of Serum Vitamin D3 Level for Forearm Fractures among Children in a Tropical Country: A Case Control Study
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Predictive Value of Serum Vitamin D3 Level for Forearm Fractures among Children in a Tropical Country: A Case Control Study

机译:热带国家儿童前臂骨折血清维生素D3水平的预测值:案例控制研究

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Orthopaedic emergency department commonly receives paediatric fractures, of which forearm fractures constitute a larger proportion with the burden greatest in lowmiddle income countries.Studies done in the temperate region found an association between forearm fractures in children and low serum vitamin D3.Some studies in our environment have shown low levels of 25-hydroxy vitamin D3 {25(OH)D} in normal Nigerian children, but the association with forearm fractures has not been studied.Aim: To determine if serum vitamin D3 level can predict the occurrence of forearm fractures in children.Materials and Methods: This was a case control study conducted over a year from January 2018 to December 2018 at a tertiary health facility in South-West Nigeria among paediatric patients.Thirty children with forearm fractures and thirty children with no forearm fractures were recruited for the study.Socio-demographic data, mechanisms of fracture, anthropometric measurements and serum 25(OH)D levels were determined.Univariate and multivariate analyses were done for the variables concerning the presence or absence of forearm fractures (dependent variable is the presence or absence of forearm fractures; independent variables include the age, sex, mechanism of injury, outdoor playing time, serum vitamin D3 level).Results: The mean serum 25(OH)D levels in the study group were significantly lower than the controls; (60.751±15.041 ng/mL and 95.506±19.489 ng/mL, respectively).There was a statistically significant relationship between the serum level of 25(OH)D and the presence of forearm fracture in children (p=0.002 and OR of 0.838).Conclusion: Children with forearm fracture have relatively lower serum vitamin D3 compared with age matched ones without fracture and they have correspondingly increased odd risks of sustaining forearm fracture.
机译:骨科急诊部门通常接受小儿骨折,其中前臂骨折构成了较大的比例,较大的低葡萄酒收入国家的负担。在温带地区进行的研究发现,儿童前臂骨折和低血清维生素D3之间的关联。我们的环境中的研究在正常的尼日利亚儿童中显示出低水平的25-羟基维生素D3 {25(OH)D},但与前臂骨折的关系尚未研究:确定血清维生素D3水平是否可以预测前臂骨折的发生儿童。材料和方法:这是从2018年1月到2018年1月到2018年12月在儿科患者中西南尼日利亚的第三节卫生机构进行的案例控制研究。招募了前臂骨折和三十个没有前臂骨折的儿童对于研究。对人口统计数据,断裂,人体测量测量和血清25(OH)D水平的机制是determined.Univariate和多变量分析对关于前臂骨折(因变量是存在或不存在前臂骨折的存在或不存在的变量进行;独立变量包括年龄,性别,伤害机制,室外演奏时间,血清维生素D3水平)。方法:研究组的平均血清25(OH)D水平显着低于对照; (分别为95.751±15.041 ng / ml和95.506±19.489 ng / ml)。血清25(OH)D之间的统计学上显着的关系以及儿童前臂骨折的存在(P = 0.002和0.838 )。结论:前臂骨折的儿童具有相对较低的血清维生素D3,与年龄匹配的血清无裂缝相比,它们相应地增加了维持前臂骨折的奇怪风险。

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