...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Clinical and Diagnostic Research >Characterisation of?Candida?Colonisation in Neonates
【24h】

Characterisation of?Candida?Colonisation in Neonates

机译：表征？念珠菌？新生儿的殖民化

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The occurrence of invasive fungal infections has increased significantly worldwide, premature infants in Neonatal Intensive Care Unit (NICU) along with other risk factors are at particular risk of these invasive fungal infections which lead to fungal septicaemia in newborns.Candidaemia is the most common form of invasive candidiasis associated with an unacceptably high mortality rates.Candida colonisation in neonates is considered the first step towards developing neonatal sepsis.Aim: To determine the prevalence of Candida colonisation and its characterisation among neonates admitted in NICU.Materials and Methods: The present study was a prospective cross-sectional study with 150 neonates included in the study.Swabs were taken from four different sites of each neonate and inoculated on Chocolate agar and Sabouraud’s Dextrose Agar (SDA) and incubated at 37°C for seven days.Candida species isolated were confirmed by gram stain, germ tube test, growth on Chromogenic (CHROM) agar and cornmeal agar.Statistical analysis was done using Statistical Package for Social Sciences (SPSS) version 11.0.Results: A total of 32 (21.3%) neonates had Candida colonisation.Twenty two (68.7%) were low birth weight and 24 (75%) were born premature.Perineum was the most common (56%) site of colonisation.Among Candida isolates, Candida tropicalis (63%) was the commonest followed by Candida parapsilosis (25%) and Candida glabrata and Candida albicans (6%).The risk factors identified were low birth weight, premature birth, use of antibiotics.Conclusion: Colonisation of preterm and low birth weight neonates by Candida species is a major risk factor and needs attention to avoid dissemination and life threatening infection.
机译：侵袭性真菌感染的发生在全球范围内显着增加，新生儿重症监护单位（Nicu）的早产儿随着其他危险因素，特别是这些侵袭性真菌感染的风险特殊风险，导致新生儿的真菌败血症.Candidaemia是最常见的与令人无法接受的高死亡率相关的侵袭性念珠菌病。新生儿的殖民达殖民化被认为是发育新生儿脓毒症的第一步：确定念珠菌殖民化的患病率及其在Nicu的新生儿的表征。目前的研究：本研究是具有在研究中包含的150个新生儿的前瞻性横截面研究。从每个新生儿的四个不同部位采用每个新生儿，并接种在巧克力琼脂和SDA的右旋糖浆（SDA）上，并在37℃下孵育七天。分离的持续物种通过革兰污染，细菌试验，生长在发色（浓度）琼脂和玉米EAL agar.statisticatistication分析是使用统计包进行社会科学版（SPSS）版本11.0.结果：共有32名（21.3％）的新生儿有念珠菌结肠酸盐。22.22（68.7％）低出生体重和24（75％）出生premature.Perineum被colonisation.Among念珠菌的最常见的（56％）的网站分离物，热带假丝酵母（63％）的，随后近平滑念珠菌（25％）和光滑念珠菌和白色念珠菌（6％）常见。该确定的危险因素是出生体重低，出生过早，抗生素的使用。结论：念珠菌物种的早产和低出生体重的殖民化是一种主要的危险因素，需要注意避免传播和危及危及危及感染。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号