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Biologic Association Annual Summit: 2020 Report

机译：生物协会年度峰会：2020年报告

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摘要

Interest and research in biologic approaches for tissue healing are exponentially growing for a variety of musculoskeletal conditions. The recent hype concerning musculoskeletal biological therapies (including viscosupplementation, platelet-rich plasma, and cellular therapies, or “stem cells”) is driven by several factors, including demand by patients promising regenerative evidence supported by substantial basic and translational work, as well as commercial endeavors that complicate the scientific and lay understanding of biological therapy outcomes. While significant improvements have been made in the field, further basic and preclinical research and well-designed randomized clinical trials are needed to better elucidate the optimal indications, processing techniques, delivery, and outcome assessment. Furthermore, biologic treatments may have potential devastating complications when proper methods or techniques are ignored. For these reasons, an association comprising several scientific societies, named the Biologic Association (BA), was created to foster coordinated efforts and speak with a unified voice, advocating for the responsible use of biologics in the musculoskeletal environment in clinical practice, spearheading the development of standards for treatment and outcomes assessment, and reporting on the safety and efficacy of biologic interventions. This article will introduce the BA and its purpose, provide a summary of the 2020 first annual Biologic Association Summit, and outline the future strategic plan for the BA.
机译：组织愈合的生物学方法的兴趣和研究是指数增长的各种肌肉骨骼条件。关于肌肉骨骼生物疗法的最近炒作（包括粘度抑制，富含血小板血浆和细胞疗法，或“干细胞”）由几个因素驱动，包括通过大量基本和翻译工作支持的再生证据的患者的需求，以及商业努力使科学和对生物治疗结果的理解复杂化。虽然在该领域取得了重大改进，但需要进一步的基本和临床前研究和精心设计的随机临床试验，以更好地阐明最佳指示，加工技术，交付和结果评估。此外，当忽略适当的方法或技术时，生物处理可能具有潜在的破坏性并发症。由于这些原因，制定了一项名为生物社会协会（BA）的科学社团的协会，以促进协调努力，并与统一的声音说话，倡导在临床实践中呼应在肌肉骨骼环境中的生物学，刺激发展治疗和结果评估标准，报告生物干预措施的安全性和有效性。本文将介绍BA及其宗旨，提供2020年第一届年度生物协会峰会的摘要，并概述了BA的未来战略计划。

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