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Survival following intentional succinylcholine injection for self-harm

机译:在故意琥珀胆碱注射后存活的自我伤害

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Succinylcholine is a short-acting depolarizing neuromuscular blocking agent. We describe a case where the above drug was employed for self-harm by a health-care worker. The patient, a 28-year-old female, was brought to the emergency department (ED) in impending respiratory arrest and altered mental status. On arrival, she had hypoxia, bradycardia, and hypotension. Although the cause for rapid deterioration in this patient was unknown, the ED physician still went ahead by resuscitating the patient’s airway, breathing, and circulation. During the course of resuscitation, information was received that an empty ampoule of succinylcholine was recovered from her bathroom. Further clinical examination and laboratory investigations led the treating physicians to suspect deliberate intravenous injection of succinylcholine. She was mechanically ventilated and monitored in the critical care unit. Targeted temperature management was initiated in the ED and was continued for 24 h. The patient was discharged from the hospital without any neurological deficits after 4 days. Patients with acute poisoning are one of the major encounters in ED, and this case highlights the possibility of anesthetic drug misuse in any health-care workers coming to the ED with sudden cardiac arrest, altered sensorium, or abnormal vitals. This is the first report describing the survival of a patient following intentional succinylcholine injection for self-harm.
机译:琥珀胆胆碱是一种短效式去极化神经肌肉阻断剂。我们描述了一种由保健工作者自我危害的上述药物的案例。患者,一名28岁的女性被带到急诊部(ED)即将发生的呼吸逮捕和改变精神状态。到达时,她患有缺氧,心动过缓和低血压。虽然本患者快速恶化的原因未知,但ED医师仍然通过重新刺激患者的气道,呼吸和循环来前进。在复苏过程中,收到了信息,从她的浴室中回收了一个空安瓿的琥珀酰胆碱。进一步的临床检查和实验室调查导致治疗医生可疑是故意静脉内注射琥珀酰胆碱。她机械通风和监测在关键护理单位。在ED中启动了目标温度管理,并继续24小时。患者在4天后从医院出院而没有任何神经缺陷。急性中毒的患者是ED的主要遭遇之一,这种情况强调了在任何突然心脏骤停,改变的传感器或异常的维生素中都有麻醉药物滥用麻醉药物滥用的可能性。这是第一个描述在有意的琥珀胆碱注射患者中患者的自我伤害。

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