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The Use of Natural Products for the Treatment of Female Sexual Dysfunction: A Systematic Review of Randomized Clinical Trials

机译:天然产品用于治疗女性性功能障碍:对随机临床试验的系统综述

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Female sexual dysfunction (FSD) affects 40% of the world’s females, most of which are disorders linked todesire or interest/excitement. Whilst all types of therapy that attempt to improve female sexual desire have long beenestablished, the results are contradictory. Objective: To analyze all available evidence to validate the effectiveness of natural therapies in thetreatment of FSD. Method: The study was registered at http://www.prospero.org (CRD42019127700). We searched the Institute for ScientificInformation Web of Knowledge, MEDLINE, Pubmed, Scopusand Cochrane databases for all articles published in peer- reviewed journals in April 2019(in any language). The PICOS standard is women with FSD; (intervention) of any type of Naturaltherapy; (outcome) primary outcome: frequency of changes, severity, and averagemean scores on sexual symptoms measured with a validated instrument, secondaryoutcome: quality of life; (study design) and randomized clinical trial (RCT). Results: The literature search strategy identified 95 articles, 81 of which wereexcluded at the different search stages.Finally, we systematically reviewed 15 RCTs, 11 of which referred to primary FSD, and four of whichanalyzed women with drug-induced FSD(DFSD). Most of them analyzed hypoactive sexual desire disorder. Although differences related to placebo were found in most people, the majority of the studies are considered to be of poor quality andlow external effectiveness. Conclusion: Although the quality of the evidence is not high,most natural product interventions appear to improve FSD, particularlyhypoactive sexual desire disorders including those categorized as primary anddrug-induced.
机译:女性性功能障碍(FSD)影响世界的40%的女性,其中大部分是疾病联系着托出或兴趣/兴奋。虽然所有类型的治疗方法都长期以来,但长期以来,结果是矛盾的。 目的:分析所有可用证据,以验证FSD的自然疗法的有效性。 方法:该研究在http://www.prospero.org注册(CRD42019127700)。我们在2019年4月(任何语言中)在同行评估的期刊上发表的所有文章(以任何语言)搜索了知识,Medline,Pubmed,Scopus和Cochrane数据库的知识,Medline,Pubmed,Scopus和Cochrane数据库研究所。 Picos标准是FSD的女性; (干预)任何类型的自然疗法; (结果)主要结果:用经过验证的仪器测量的性症状的变化,严重程度和平均评分,中学:生活质量; (研究设计)和随机临床试验(RCT)。 结果:文献搜索策略确定了95篇文章,其中81篇,其中81篇在不同的搜索阶段。最后,我们系统地审查了15个RCT,其中11名,其中11名,其中11名提到了初级FSD,其中四种含有药物诱导的FSD的含量( DFSD)。他们中的大多数分析了性欲的欲望障碍。尽管在大多数人中发现与安慰剂有关的差异,但大多数研究被认为是质量差的弱势外部效果。 结论:虽然证据的质量不高,但大多数天然产品干预似乎改善了FSD,尤其活跃的性欲障碍,包括分类为初级安德鲁夫诱导的疾病。

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