...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Frontiers in Medicine >Multi-Atlas MRI-Based Striatum Segmentation for 123 I-FP-CIT SPECT (DAT-SPECT) Compared With the Bolt Method and SPECT-Atlas-Based Segmentation Method Toward the Accurate Diagnosis of Parkinson's Disease/Syndrome
【24h】

Multi-Atlas MRI-Based Striatum Segmentation for 123 I-FP-CIT SPECT (DAT-SPECT) Compared With the Bolt Method and SPECT-Atlas-Based Segmentation Method Toward the Accurate Diagnosis of Parkinson's Disease/Syndrome

机译：基于多阿特拉斯MRI的纹章分割，用于123 I-FP-CIT SPECT（DAT-SPECT）与基于螺栓法和基于SPECT-ATLAS的分段方法进行了准确诊断帕金森病/综合征的准确诊断

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Aims: This study aimed to analyze the performance of multi-atlas MRI-based parcellation for 123 I-FP-CIT SPECT (DAT-SPECT) in healthy volunteers. The proposed method was compared with the SPECT-atlas-based and Bolt methods. 18 F-FE-PE2I-PET (DAT-PET) was used as a reference. Methods: Thirty healthy subjects underwent DAT-SPECT, DAT-PET, and 3D-T1WI-MRI. We calculated the striatum uptake ratio (SUR/SBR), caudate uptake ratio (CUR), and putamen uptake ratio (PUR) for DAT-SPECT using the multi-atlas MRI-based method, SPECT-atlas-based method, and Bolt method. In the multi-atlas MRI-based method, the cerebellum, occipital cortex, and whole-brain were used as reference regions. The correlation of age with DAT-SPECT activity and the correlations of SUR/SBR, CUR, and PUR between DAT-SPECT and DAT-PET were calculated by each of the three methods. Results: The correlation between age and SUR/SBR for DAT-SPECT based on the multi-atlas MRI-based method was comparable to that based on the SPECT-atlas-based method ( r = ?0.441 to ?0.496 vs. ?0.488). The highest correlation between DAT-SPECT and DAT-PET was observed using the multi-atlas MRI-based method with the occipital lobe defined as the reference region compared with the SPECT-atlas-based and Bolt methods (SUR, CUR, and PUR: 0.687, 0.723, and 0.676 vs. 0.698, 0.660, and 0.616 vs. 0.655). Conclusion: Multi-atlas MRI-based parcellation with the occipital lobe defined as the reference region was at least comparable to the clinical methods.
机译：目的：本研究旨在分析健康志愿者的123 I-FP-CIT SPECT（DAT-SPECT）的多阿特拉斯MRI的局部的表现。将所提出的方法与基于SPECT-ATLAS和螺栓方法进行比较。 18 F-Fe-PE2I-PET（DAT-PET）用作参考。方法：30个健康受试者接受了DAT-SPECT，DAT-PET和3D-T1WI-MRI。使用基于多阿特拉斯MRI的方法，SPECT-ATLAS的方法和螺栓法。在基于多阿特拉斯MRI的方法中，使用小脑，枕骨皮质和全脑作为参考区域。通过三种方法中的每种方法计算年龄与DAT-SPECT活性和SUR / SBR，CUR，CUR和PUR的相关性的相关性。结果：基于多阿特拉斯MRI的方法的年龄和SUR / SBR之间的相关性与基于SPECT-ATLAS的方法（R = 0.441至0.496 Vs. <0.488）相当。与基于SPECT-ATLAS和螺栓方法（SUR，CUR和PUR： 0.687,0.723和0.676 vs.0.698,0.660和0.616 Vs. 0.655）。结论：多阿特拉斯MRI基对枕叶定义为参考区的局部局部至少与临床方法相当。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号