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首页> 外文期刊>Open Journal of Ophthalmology >Macular Morphology in Patients with Retinopathy of Prematurity
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Macular Morphology in Patients with Retinopathy of Prematurity

机译：早熟视网膜病变的黄斑形态

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Purpose: To investigate macular morphology by spectral domain optical coherence tomography (SDOCT) in children with history of the retinopathy of prematurity (ROP). Materials and methods: In this cross-sectional study we included 35 eyes of 18 patients, aged 4 to 8 years, with history of ROP. Twenty-one eyes had received treatment for type 1 pre-threshold ROP. The others showed spontaneous regression of the disease. A 7 × 7-mm retinal area was sampled using a 3-dimensional scanning protocol with high-resolution spectral domain optical coherence tomography (SOCT Copernicus REVO). The central foveal thickness, mean macular thickness, macular volume and foveal depression were measured. The macular anatomy and the foveal contour were examined. Results: The mean birth weight was 1338.29 ± 324.05 grams. Mean gestational age at birth was 29.37 ± 2.07 weeks. Twenty-one eyes were treated with laser or cryotherapy. All of them showed regression of the disease. The mean best corrected visual acuity was 20/28. The average central foveal thickness was 262.26 ± 37.39, with 68.57% of preterm > 240 μm and 22.86% > 220 μm. In all eyes, the foveal contour is abnormal. A foveal depression was absent in 25 eyes (71%). Conclusion: In the majority of children with a history of ROP, we found changes in macular morphology, including retention of inner retinal layers and absent foveal depression. In our study foveal hypoplasia was associated with good functional outcome.
机译：目的：通过谱系域光学相干断层扫描（SDOCT）在早产儿（ROP）视网膜病变的历史中，通过光谱域光学相干断层扫描（SDOCT）来研究黄斑形态。材料和方法：在这种横断面研究中，我们包含35只18名患者，年龄在4至8岁，历史悠久。二十一只眼睛已经接受了1型预阈值ROP的治疗。其他人表现出自发的疾病。使用具有高分辨率谱域光学相干断层扫描（SOCT Copernicus Revo）的三维扫描协议进行采样7×7mm视网膜区域。测量中心芯片厚度，平均黄斑厚度，黄斑体积和污水抑制。检查黄斑解剖和心脏轮廓。结果：平均出生体重为1338.29±324.05克。出生时的平均胎龄为29.37±2.07周。用激光或冷冻疗法治疗二十一只眼睛。所有这些都表现出对疾病的回归。平均最佳矫正视力是20/28。平均中央芯片厚度为262.26±37.39，最小值68.57％>240μm和22.86％220μm。在所有的眼睛中，心脏轮廓异常。 25只眼中不存在污水抑制（71％）。结论：在大多数患有ROP历史的儿童中，我们发现黄斑形态的变化，包括保留内视网膜层和缺乏污肠抑郁症。在我们的研究中，心脏病发育性与良好的功能结果有关。

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