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首页> 外文期刊>Journal of Behavioral and Brain Science >Maternal Cosmetics and the Risk of Autism: A Case-Control Pilot Study
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Maternal Cosmetics and the Risk of Autism: A Case-Control Pilot Study

机译：孕产妇化妆品和自闭症的风险：案例控制试验研究

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Background: There has been much debate and inquiry surrounding the nature of the increase in prevalence of autism spectrum disorder (ASD). There are many environmental risk factors that have been postulated to be associated with the development of ASD. Cosmetic products are widely used in daily life. The aim of this study was to clarify whether maternal cosmetics usage is a risk factor of ASD. Patients and Methods: The present work was a cross sectional case-control study. Fifty eight mothers with children, who have been diagnosed with ASD by meeting the DMS-5 criteria, were compared with 49 mothers with neurotypical children. The mothers were asked to complete a short questionnaire comprised their use of cosmetics outside of pregnancy and changes in use during pregnancy. Results: No statistically significant difference was found between cases and controls as regard the overall usage of cosmetics. Indoors usage of makeup was significantly higher among mothers with autistic children than mothers of controls (p = 0.36). The duration of cosmetics usage was significantly higher among the mothers of controls than mothers with autistic children (p = 0.011). Eyes and lips makeup were the most frequent of makeup type among mothers with autistic children and controls while hair protein or keratin were the least frequent of makeup type among both groups. The number of women who reported the usage of lips makeup was significantly higher among the mothers of controls than those with autistic children (p = 0.024). The number of mothers with autistic children who reported “no change” as regard the usage pattern during pregnancy was significantly higher than those of the controls (p = 0.042). Conclusions: According to our results, cosmetics could not be considered as a risk factor for ASD. Further understanding of this issue requires future studies with different designs.
机译：背景：围绕自闭症谱系疾病（ASD）患病率增加的争论和询问。有许多环境风险因素已被假设与ASD的发展有关。化妆品广泛用于日常生活中。本研究的目的是阐明孕产妇化妆品是否是ASD的危险因素。患者和方法：本作本作是横截面案例对照研究。通过符合DMS-5标准诊断为ASD的儿童五十八名母亲，与49名母亲与神经典型的儿童进行比较。母亲被要求完成一项简短的问卷，包括他们在怀孕之外使用化妆品和怀孕期间使用的变化。结果：在案件和控制之间没有发现统计学上的差异，以便将化妆品的整体用法进行整体使用。在母亲的母亲与自闭症儿童的母亲的使用明显高于控制母亲（P = 0.36）。与自闭症儿童的母亲相比，化妆品的持续时间明显高于母亲（P = 0.011）。眼睛和嘴唇化妆是具有自闭症儿童和对照组的母亲中最常见的化妆类型，而头发蛋白或角蛋白是两个组中的化妆型的最常用。涉嫌使用嘴唇化妆的妇女人数在对照组的母亲比自闭症儿童的母亲中显着更高（P = 0.024）。报告怀孕期间的使用模式的自闭症儿童的母亲数量明显高于对照（P = 0.042）。结论：根据我们的结果，化妆品不能被视为ASD的危险因素。进一步了解这个问题需要未来的不同设计研究。

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