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首页> 外文期刊>Journal of International Medical Research >Prevalence of and risk factors for high-altitude hyperuricaemia in Bai individuals: a cross-sectional study
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Prevalence of and risk factors for high-altitude hyperuricaemia in Bai individuals: a cross-sectional study

机译：白人高原高海藻血症患病率和危险因素：横断面研究

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摘要

Objective Hyperuricaemia is common in Bai individuals; however, its prevalence remains unclear. This work aimed to investigate high-altitude hyperuricaemia prevalence and risk factors in Bai individuals. Methods All eligible participants of Bai ethnicity (aged ≥18 years and undergoing routine medical examination at the People’s Hospital of Jianchuan County between January and December 2019) were consecutively enrolled. Demographic and laboratory data were collected to investigate hyperuricaemia prevalence and associated risk factors. Results A total of 1393 participants were assessed, comprising 345 (24.8%) with hyperuricaemia showing a male predominance (287/865 [33.2%] males versus 58/528 [11.0%] females). Hyperuricaemia prevalence was significantly higher in participants aged ≥50 years (100/332 [30.1%]) versus those aged 30–40 years (59/308 [19.2%]), and in overweight/obese individuals compared with those showing an underweight or normal body mass index (BMI; 267/885 [30.2%] versus 78/508 [15.4%]). Finally, haemoglobin concentrations and serum uric acid levels were positively correlated. Conclusion Besides traditional risk factors, including age, sex and BMI, polycythaemia due to prolonged exposure to high altitude may also cause hyperuricaemia in Bai individuals residing in Yunnan Province.
机译：客观的过度尿素在白人人中是常见的;然而，它的流行仍然不清楚。这项工作旨在调查白人个人的高海拔高尿血症患病率和危险因素。方法全部聘请Bai族族（≥18岁及2019年1月12日）之间的人民医院（≥18岁及经营的常规体检）进行了连续注册。收集了人口统计和实验室数据，以调查Heaturecaremia患病率和相关的危险因素。结果共评估了1393名参与者，包含345（24.8％）的高掩果，显示男性优势（287/865 [33.2％]男性，女性雌性）。 ≥50岁的参与者（100/332 [30.1％]）与30-40岁（59/308 [19.2％]）的参与者，以及超重/肥胖个体的参与者显着提高，与那些表现不重要的人（59/308）和超重/肥胖的人正常体重指数（BMI; 267/885 [30.2％]对78/508 [15.4％]）。最后，血红蛋白浓度和血清尿酸水平呈正相关。结论除了传统风险因素，包括年龄，性别和BMI，由于长期暴露于高海拔的多循环症也可能导致云南百年白人的高尿素血症。

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