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The Roseobacter-Group Bacterium Phaeobacter as a Safe Probiotic Solution for Aquaculture

机译:Rosebacter-Group Bacterium phaeobacter作为水产养殖的安全益生菌溶液

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Phaeobacter inhibens has been assessed as a probiotic bacterium for application in aquaculture. Studies addressing the efficacy and safety indicate that P. inhibens maintains its antagonistic activity against pathogenic vibrios in aquaculture live cultures (live feed and fish egg/larvae) while having no or a positive effect on the host organisms and a minor impact on the host microbiomes. While P. inhibens produces antibacterial and algicidal compounds, no study has so far found a virulent phenotype of P. inhibens cells against higher organisms. Additionally, an in silico search for antibiotic resistance genes using published genomes of representative strains did not raise concerns regarding the risk for antimicrobial resistance. P. inhibens occurs naturally in aquaculture systems, supporting its safe usage in this environment. In conclusion, at the current state of knowledge, P. inhibens is a “safe-to-use” organism.
机译:已经评估了Phaeobacter抑制作为在水产养殖中应用的益生菌细菌。 解决疗效和安全性的研究表明,P.抑制在水产养殖活培养(活饲料和鱼蛋/幼虫)中对致病性血管的拮抗活性保持不存在,同时对宿主生物和对宿主微生物的微生物产生微生物影响 。 虽然P.抑制产生抗菌和杀虫剂化合物,但到目前为止没有研究毒性表型对抑制较高生物的毒性表型。 另外,在使用发表的代表性菌株的出版基因组的抗生素抗性基因中的硅搜索并未提高关于抗微生物抗性风险的担忧。 P.抑制在水产养殖系统中自然发生,支持其在这种环境中的安全使用情况。 总之,在目前的知识状态下,P.抑制是一种“安全使用”的生物体。

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