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Individualized PID Tuning for Maintenance of General Anesthesia with Propofol

机译:用异丙酚维持全身麻醉的个性化PID调整

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In this paper we investigate a novel tuning methodology for a patient-individualized selection of the parameters of a proportional-integral-derivative (PID) controller that regulates the maintenance phase of general anesthesia. In particular, the knowledge of demographic data is exploited to determine the values of the parameters for each specific patient. The proposed approach is focused on the closed-loop administration of propofol by using the Bispectral Index Scale as controlled variable. Simulation results suggest that, with respect to a previously devised population-based PID tuning approach, the new methodology is more robust with respect to both intra-patient and inter-patient variability, at the cost of a slight decrement in the controller bandwidth.
机译:在本文中,我们研究了一种小型调谐方法,用于患者个性化的患者互联的参数,其比例 - 积分衍生物(PID)控制器的参数调节全身麻醉的维持阶段。 特别地,利用对人口统计数据的知识来确定每个特定患者的参数的值。 所提出的方法专注于通过使用双光谱指数刻度作为受控变量的闭环施用异丙酚。 仿真结果表明,关于先前设计的基于人口的PID调谐方法,新方法对于患者内部患者和患者间的互补性更强,以略微减少控制器带宽的成本。

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