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首页> 外文期刊>PLoS One >Promoters and inhibitors of treatment adherence among HIV/AIDS patients receiving antiretroviral therapy in Ghana: Narratives from an underserved population
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Promoters and inhibitors of treatment adherence among HIV/AIDS patients receiving antiretroviral therapy in Ghana: Narratives from an underserved population

机译：艾滋病毒/艾滋病患者在加纳接受抗逆转录病毒治疗的患者治疗粘附的启动子和抑制剂：来自欠缺人口的叙事

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摘要

Adherence to antiretroviral therapy (ART) is essential to achieving an improved cluster of differentiation-4 (CD4) count, viral load, and quality of life while preventing drug resistance. Medication adherence among people living with Human Immunodeficiency Virus (HIV) is influenced by different factors. Several studies have identified adherence promoters and inhibitors that emanate from the internal and external environment. We conducted six (6) individual in-depth interviews and three (3) focus group discussions to explore adherence behaviour among patients diagnosed with HIV in a teaching hospital in Accra, Ghana. Participants were drawn from the intervention arm of a mobile phone adherence intervention program. They had been enrolled in the study for at least six (6) months before the interviews are conducted. Results revealed that participants adhered to treatment irrespective of prompts from significant others. Adherence promoters included perception of ART as part of daily routines, benefits of the ART, awareness of regimen, access to food, and transparency. Adherence inhibitors were forgetfulness, secrecy, waiting time, religious beliefs, and sleep. People living with HIV (PLWHIV) have the personal motivation to take medication; however, negative perceptions about HIV must be addressed to ensure optimum adherence behaviour.
机译：坚持抗逆转录病毒治疗（ART）对于实现改进的分化-4（CD4）计数，病毒载量和寿命质量的必然，同时防止耐药性。使用人类免疫缺陷病毒（HIV）的人们之间的药物依从性受到不同因素的影响。几项研究鉴定了来自内部和外部环境的粘附启动子和抑制剂。我们进行了六（6）个个人深入的访谈和三（3）个焦点小组讨论，以探讨患有艾滋病毒在加纳的教学医院患者患者的依从性行为。参与者是从手机依从性干预计划的干预臂中汲取的。在采访前至少六（6）个月，他们已经在研究中注册了至少六（6）个月。结果表明，与会者遵守治疗，无论有重要其他人的提示如何。粘附启动子包括作为日常生活的一部分，艺术的益处，方案意识，食物和透明度的益处。粘附抑制剂是忘记，保密，等待时间，宗教信仰和睡眠。与艾滋病毒（Plwhi​​v）一起生活的人具有服用药物的个人动机;然而，必须解决对艾滋病毒的负面看法，以确保最佳依从性行为。

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