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首页> 外文期刊>BMC Medical Informatics and Decision Making >Pragmatic MDR: a metadata repository with bottom-up standardization of medical metadata through reuse
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Pragmatic MDR: a metadata repository with bottom-up standardization of medical metadata through reuse

机译:语用MDR:通过重用的具有自下而上标准化的元数据存储库

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The variety of medical documentation often leads to incompatible data elements that impede data integration between institutions. A common approach to standardize and distribute metadata definitions are ISO/IEC 11179 norm-compliant metadata repositories with top-down standardization. To the best of our knowledge, however, it is not yet common practice to reuse the content of publicly accessible metadata repositories for creation of case report forms or routine documentation. We suggest an alternative concept called pragmatic metadata repository, which enables a community-driven bottom-up approach for agreeing on data collection models. A pragmatic metadata repository collects real-world documentation and considers frequent metadata definitions as high quality with potential for reuse. We implemented a pragmatic metadata repository proof of concept application and filled it with medical forms from the Portal of Medical Data Models. We applied this prototype in two use cases to demonstrate its capabilities for reusing metadata: first, integration into a study editor for the suggestion of data elements and, second, metadata synchronization between two institutions. Moreover, we evaluated the emergence of bottom-up standards in the prototype and two medical data managers assessed their quality for 24 medical concepts. The resulting prototype contained 466,569 unique metadata definitions. Integration into the study editor led to a reuse of 1836 items and item groups. During the metadata synchronization, semantic codes of 4608 data elements were transferred. Our evaluation revealed that for less complex medical concepts weak bottom-up standards could be established. However, more diverse disease-related concepts showed no convergence of data elements due to an enormous heterogeneity of metadata. The survey showed fair agreement (Kalpha?=?0.50, 95% CI 0.43–0.56) for good item quality of bottom-up standards. We demonstrated the feasibility of the pragmatic metadata repository concept for medical documentation. Applications of the prototype in two use cases suggest that it facilitates the reuse of data elements. Our evaluation showed that bottom-up standardization based on a large collection of real-world metadata can yield useful results. The proposed concept shall not replace existing top-down approaches, rather it complements them by showing what is commonly used in the community to guide other researchers.
机译:各种医疗文档通常导致不兼容的数据元素,可以阻碍机构之间的数据集成。标准化和分发元数据定义的常见方法是具有自上而下标准化的ISO / IEC 11179标准的元数据存储库。但是,据我们所知,重复使用公开可访问的元数据存储库的内容来创建案例报告表单或例行文档并不是常见的做法。我们建议替代概念称为语用元数据存储库,该概念使社区驱动的自下而上方法能够同意数据收集模型。务实的元数据存储库收集现实世界文档,并将频繁的元数据定义视为高质量,具有重用潜力。我们实施了一个概念应用程序的实用元数据存储库证明,并通过医疗数据模型的门户填充了医疗表格。我们在两种用例中应用了这个原型,以展示其重用元数据的功能:第一,集成到研究编辑器中,以了解数据元素的建议,而第二个机构之间的元数据同步。此外,我们评估了原型的自下而上标准的出现,两位医疗数据管理人员评估了24个医学概念的质量。生成的原型包含466,569个唯一的元数据定义。集成到研究编辑器导致重用1836项和项目组。在元数据同步期间,传输了4608个数据元素的语义代码。我们的评价显示,对于不太复杂的医学概念,可以建立弱自下而上标准。然而,由于元数据的巨大异质性,更多样化的疾病相关概念显示出数据元素的收敛性。该调查显示了公平的协议(Kalpha?= 0.50,95%CI 0.43-0.56),用于良好的自下而上标准。我们展示了医疗文档的务实元数据储存库概念的可行性。原型在两个用例中的应用表明它有助于重用数据元素。我们的评价显示,基于大量现实世界元数据的自下而上标准化可以产生有用的结果。所提出的概念不得取代现有的自上而下方法,而是通过展示社区常用以指导其他研究人员来补充它们。

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