...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>BMC Gastroenterology >Primary squamous cell carcinoma of the pancreas with a large pseudocyst of the pancreas as the first manifestation: a rare case report and literature review
【24h】

Primary squamous cell carcinoma of the pancreas with a large pseudocyst of the pancreas as the first manifestation: a rare case report and literature review

机译：胰腺的主要鳞状细胞癌与胰腺的大伪症作为第一个表现：罕见的报告和文献综述

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Primary squamous cell carcinoma (SCC) of the pancreas with pseudocysts, especially diagnosed by endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA), is extremely rare. A 64-year-old man was admitted to our department for abdominal distension. Two months ago, he experienced abdominal pain for 1?day and was diagnosed with acute pancreatitis in another hospital. After admission, laboratory tests showed the following: amylase 400 U/L, lipase 403 U/L, and carbohydrate antigen 19–9 (CA19-9) 347 U/mL. Abdominal computed tomography (CT) revealed pancreatitis with a pseudocyst with a diameter measuring 7?cm. During linear EUS, a large pseudocyst (5.4?×?5.2?cm) was observed in the pancreatic body. EUS-FNA was performed. We obtained specimens for histopathology and placed a plastic stent through the pancreas and stomach to drain the pseudocyst. Puncture fluid examination revealed the following: CA19-9??12,000 U/mL carcinoembryonic antigen (CEA) 7097.42?ng/ml, amylase 27,145.3 U/L, and lipase??6000 U/L. Cytopathology revealed an abnormal cell mass, and cancer was suspected. Furthermore, with the result of immunohistochemistry on cell mass (CK (? ), P40 (? ), p63 (? ), CK7 (?) and Ki-67 (30%)), the patient was examined as squamous cell carcinoma (SCC). However, the patient refused surgery, radiotherapy and chemotherapy. After drainage, the cyst shrank, but the patient died 3?months after diagnosis due to liver metastasis and multiple organ failure. For patients with primary pancreatic pseudocysts with elevated serum CEA and CA19-9 levels, we should not rule out pancreatic cancer, which may also be a manifestation of primary pancreatic SCC. EUS-FNA is helpful for obtaining histopathology and cytology and thus improving diagnostic accuracy.
机译：胰腺胰腺的主要鳞状细胞癌（SCC），尤其是通过内窥镜超声引导的细针吸入（EUS-FNA）诊断，非常罕见。一名64岁的男子被呼吁我们腹胀。两个月前，他经历了腹痛1？日，并被诊断出在另一家医院的急性胰腺炎。入学后，实验室测试显示以下：淀粉酶400 U / L，脂肪酶403 U / L和碳水化合物抗原19-9（CA19-9）347 U / mL。腹部计算断层扫描（CT）揭示了胰腺炎，具有伪细胞，直径为7Ω厘米。在线性EUS期间，在胰腺体中观察到大的伪变性（5.4？×5.2℃）。进行EUS-FNA。我们获得了组织病理学的标本，并通过胰腺和胃放置了塑料支架，以排出伪变性。穿刺液检查显示以下：Ca19-9？＆α19,000U / ml癌胚抗原（CEA）7097.42α.NG/ mL，淀粉酶27,145.3u / L和脂肪酶？6000 U / L.细胞病变揭示了细胞质量异常，并且怀疑癌症。此外，通过免疫组织化学在细胞质量（CK（α），p40（α），p63（β），CK7（β）和Ki-67（30％））中，检查为鳞状细胞癌（SCC ）。然而，患者拒绝手术，放射治疗和化疗。排水后，囊肿萎缩，但患者在肝转移和多器官衰竭引起的诊断后诊断3个月。对于患有血清CEA和CA19-9水平升高的原发性胰腺假囊性的患者，我们不应排除胰腺癌，也可能是初级胰腺SCC的表现。 EUS-FNA有助于获得组织病理学和细胞学，从而提高诊断准确性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号