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首页> 外文期刊>BMC Gastroenterology >Higher frailty burden in older adults with chronic constipation
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Higher frailty burden in older adults with chronic constipation

机译：慢性便秘的老年人的更高脆弱负担

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Despite constipation being a common clinical condition in older adults, the clinical relevance of constipation related to frailty is less studied. Hence, we aimed to investigate the association between chronic constipation (CC) and frailty in older adults. This is a cross-sectional analysis of a population-based, prospective cohort study of 1278 community-dwelling older adults in South Korea. We used the Rome criteria to identify patients with irritable bowel syndrome with predominant constipation (IBS-C) and functional constipation (FC). We investigated whether participants consistent with the criteria for IBS-C and FC had CC. Frailty was assessed using the Cardiovascular Health Study (CHS) frailty phenotype. In the study population with a mean age of 75.3?±?6.3?years, 136 (10.7%) had CC. The participants with CC were older, had higher medication burdens, and had worse physical performances compared to those without CC (All P??.05). By association analysis, the prevalence of CC was associated with frailty by the CHS criteria (P??.001). The CHS frailty score was associated with the presence of CC by the univariate logistic regression analysis and the multivariate analysis adjusted for age, sex, and multimorbidity. Frailty was associated with CC in community-dwelling older people, suggesting that constipation should be considered as an important geriatric syndrome in clinical practice concerning frail older adults.
机译：尽管便秘是老年人的常见临床状况，但仍然较少与脆弱相关的便秘临床相关性。因此，我们旨在调查老年成年人慢性便秘（CC）和脆弱之间的关联。这是对韩国1278名社区住宅年龄较大的成年人的基于人口的，前瞻性队列研究的横截面分析。我们利用罗马标准鉴定具有主要便秘（IBS-C）和功能性便秘（FC）的肠易肠综合征患者。我们调查了与IBS-C和FC标准一致的参与者是否具有CC。使用心血管健康研究（CHS）脆弱的表型评估脆弱。在学习人口中，平均年龄为75.3？±6.3？年，136（10.7％）有CC。 CC的参与者年龄较大，药物负担较高，与没有CC的人相比，物理性能更差（所有P？＆ 05）。通过关联分析，CC的患病率与CHS标准（p≤00）的脆弱相关。 CHS Frailty评分与单变量逻辑回归分析和年龄，性别和多药物的多变量分析和多变量分析的存在相关。脆弱在社区住宅的老年人中与CC有关，这表明便秘应该被视为关于脆弱年龄成年人的临床实践中的重要老年综合征。

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