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首页> 外文期刊>BMC Gastroenterology >Clinical characteristics of acute pancreatitis in children: a single-center experience in Western China
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Clinical characteristics of acute pancreatitis in children: a single-center experience in Western China

机译：儿童急性胰腺炎的临床特征：中国西部的单中心体验

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The diagnosis of pediatric pancreatitis has been increasing over the last 20?years. We aimed to compare the clinical characteristics for pediatric acute pancreatitis (AP) with adult AP, and investigate the risk factor for acute recurrent pancreatitis (ARP) in children. From June 2013 to June 2019, a total of 130 pediatric patients with AP at the inpatient database were enrolled. Univariate analysis and multivariate Cox regression analysis were performed to identify the risk factors for ARP in children. Major etiologic factors in 130 patients were biliary (31.5%), idiopathic (28.5%). The etiology of pancreatitis in children was markedly different from that in adults (p??0.001). Compared with the adult patients, the pediatric patients had significantly lower severity (p?=?0.018) and occurrence rate of pancreatic necrosis (p?=?0.041), SIRS (p?=?0.021), acute peripancreatic fluid collection (p?=?0.014). Univariate and Multivariate Cox regression analysis showed that female (p?=?0.020; OR 3.821; 95% CI 1.231–11.861), hypertriglyceridemia (p?=?0.045; OR 3.111; 95% CI 1.024–9.447), pancreatic necrosis (p?=?0.023; OR 5.768; 95% CI 1.278–26.034) were the independent risk factors of ARP. Hypertriglyceridemia AP had the highest risk of recurrence compared to other etiology (p?=?0.035). Biliary and idiopathic disease were the major etiologies of AP in children. Children have simpler conditions than adults. Female, hypertriglyceridemia, and pancreatic necrosis were associated with the onset of ARP.
机译：在过去的20年里，儿科胰腺炎的诊断已经增加了。我们的旨在比较具有成人AP的小儿急性胰腺炎（AP）的临床特征，并研究儿童急性复发性胰腺炎（ARP）的危险因素。从2013年6月到2019年6月，在住院后数据库中共有130名具有AP的儿科患者。进行单变量分析和多元COX回归分析，以确定儿童ARP的危险因素。 130名患者的主要病因因素是胆道（31.5％），特发性（28.5％）。儿童胰腺炎的病因与成人中的胰腺炎（P 1 0.001）显着不同。与成年患者相比，儿科患者的严重程度显着降低（P？= 0.018），胰腺坏死的发生率（p？= 0.041），sirs（p？= 0.021），急性围绕百倍普通液收集（p？ =？0.014）。单变量和多变量的Cox回归分析显示，雌性（p？= 0.020;或3.821; 95％CI 1.231-11.861），高甘油脂血症（P？= 0.045;或3.111; 95％CI 1.024-9.447），胰腺坏死（P.447），胰腺坏死（P ？=？0.023;或5.768; 95％CI 1.278-26.034）是ARP的独立风险因素。与其他病因相比，高甘油脂血症AP具有最高的复发风险（P？= 0.035）。胆道和特发性疾病是儿童AP的主要病因。儿童的条件比成年人更简单。女性，高甘油三酯血症和胰腺坏死与ARP发作有关。

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