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Leveraging gains from African Center for Integrated Laboratory Training to combat HIV epidemic in sub-Saharan Africa

机译:利用非洲综合实验室培训中的非洲综合实验室培训的收益,以便在撒哈拉以南非洲开展艾滋病毒疫情

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In sub-Saharan Africa, there is dearth of trained laboratorians and strengthened laboratory systems to provide adequate and quality laboratory services for enhanced HIV control. In response to this challenge, in 2007, the African Centre for Integrated Laboratory Training (ACILT) was established in South Africa with a mission to train staffs from countries with high burdens of diseases in skills needed to strengthen sustainable laboratory systems. This study was undertaken to assess the transference of newly gained knowledge and skills to other laboratory staff, and to identify enabling and obstructive factors to their implementation. We used Kirkpatrick model to determine training effectiveness by assessing the transference of newly gained knowledge and skills to participant’s work environment, along with measuring enabling and obstructive factors. In addition to regular course evaluations at ACILT (pre and post training), in 2015 we sent e-questionnaires to 867 participants in 43 countries for course participation between 2008 and 2014. Diagnostics courses included Viral Load, and systems strengthening included strategic planning and Biosafety and Biosecurity. SAS v9.44 and Excel were used to analyze retrospective de-identified data collected at six months pre and post-training. Of the 867 participants, 203 (23.4%) responded and reported average improvements in accuracy and timeliness in Viral Load programs and to systems strengthening. For Viral Load testing, frequency of corrective action for unsatisfactory proficiency scores improved from 57 to 91%, testing error rates reduced from 12.9% to 4.9%; 88% responders contributed to the first national strategic plan development and 91% developed strategies to mitigate biosafety risks in their institutions. Key enabling factors were team and management support, and key obstructive factors included insufficient resources and staff’s resistance to change. Training at ACILT had a documented positive impact on strengthening the laboratory capacity and laboratory workforce and substantial cost savings. ACILT’s investment produced a multiplier effect whereby national laboratory systems, personnel and leadership reaped training benefits. This laboratory training centre with a global clientele contributed to improve existing laboratory services, systems and networks for the HIV epidemic and is now being leveraged for COVID-19 testing that has infected 41,332,899 people globally.
机译:在撒哈拉以南非洲,有训练有素的实验室和加强实验室制度,为增强的HIV控制提供了适当和优质的实验室服务。为应对这一挑战,2007年,非洲综合实验室培训中心(ACILT)是在南非建立的,该使命是从加强可持续实验室系统所需的技能所需的技能高负担的国家培训员工的使命。本研究旨在评估新获得知识和技能的转移到其他实验室工作人员,并确定其实施的能力和阻碍因素。我们使用Kirkpatrick模型来通过评估新获得的知识和技能对参与者的工作环境以及测量的能力和阻碍因素来确定培训效果。除了常规课程评估外,2015年,我们在2008年至2014年期间向43个国家发送了电子问卷到43个国家的867名参与者。诊断课程包括病毒载量,以及加强制度加强战略规划和生物安全和生物安全。 SAS V9.44和Excel用于分析预先和培训后六个月收集的回顾性的去鉴定数据。在867名参与者中,203名(23.4%)回应并报告了病毒载荷计划中的准确性和及时性的平均改善和系统加强。对于病毒载载测试,纠正效力频率的频率从57%增加到91%,测试误差率从12.9%降至4.9%; 88%的响应者促成了第一个国家战略计划的发展,91%的制定战略,以减轻其机构的生物安全风险。关键的使能因素是团队和管理支持,关键的阻碍因素包括资源不足,员工对变革的抵抗力。 ACILT培训对加强实验室能力和实验室劳动力以及大量成本节省的积极影响。 ACILT的投资产生了乘数效果,由此国家实验室系统,人员和领导力得到了培训效益。该实验室培训中心具有全球客户,有助于改善艾滋病病毒疫情的现有实验室服务,系统和网络,现在正在为Covid-19的测试而被杠杆化,这些测试已经在全球范围内感染了41,332,899人。

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