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首页> 外文期刊>BMC Microbiology >Prevalence of nontuberculous mycobacteria in a tertiary hospital in Beijing, China, January 2013 to December 2018
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Prevalence of nontuberculous mycobacteria in a tertiary hospital in Beijing, China, January 2013 to December 2018

机译：2018年1月至2018年12月，中国北京大专患者在北京大学医院患病率

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To investigate the species distribution of non-tuberculous mycobacteria (NTM) among tuberculosis (TB) specimens collected from January 2013 to December 2018 at Peking Union Medical Hospital (Beijing), China. NTM species identification was carried out by DNA microarray chip. Mycobacterial species were detected in 1514 specimens from 1508 patients, among which NTM accounted for 37.3% (565/1514), increasing from a proportion of 15.6% in 2013 to 46.1% in 2018 (P??0.001). Among the 565 NTM positive specimens, the majority (55.2%) were from female patients. Furthermore, patients aged 45–65?years accounted for 49.6% of the total patients tested. Among 223 NTM positive specimens characterized further, the majority (86.2%) were from respiratory tract, whilst 3.6 and 3.1% were from lymph nodes and pus, respectively. Mycobacterium intracellulare (31.8%) and Mycobacterium chelonae / Mycobacterium abscessus (21.5%) were the most frequently detected species, followed by M. avium (13.5%), M. gordonae (11.7%), M. kansasii (7.6%), and others. The proportion of NTM among mycobacterial species detected in a tertiary hospital in Beijing, China, increased rapidly from year 2013 to 2018. Middle-aged patients are more likely to be infected with NTM, especially females. Mycobacterium intracellulare and Mycobacterium chelonae/ Mycobacterium abscessus were the most frequently detected NTM pathogens. Accurate and timely identification of NTM is important for diagnosis and treatment.
机译：探讨从2013年1月到2018年1月收集的结核病（TB）标本中非结核性分枝杆菌（NTM）的物种分布在2018年至2018年12月北京联合医科医院（北京）。 NTM物种鉴定由DNA微阵列芯片进行。从1508名患者的1514个标本中检测到分枝杆菌物种，其中NTM占37.3％（565/1514），从2013年的比例增加了15.6％至2018年的46.1％（p？＆？0.001）。在565个NTM阳性标本中，大多数（55.2％）来自女性患者。此外，45-65岁的患者占测试过的患者的49.6％。在223个NTM阳性标本中，其特征在于，大多数（86.2％）来自呼吸道，分别为3.6和3.1％，分别来自淋巴结和脓液。分枝杆菌细胞内（31.8％）和脓毒杆菌/分枝杆菌脓肿（21.5％）是最常检测到的物种，其次是M. Avium（13.5％），M.Gordonae（11.7％），M. kansasii（7.6％），和其他。中国北京大专中检测到的分枝杆菌物种中NTM的比例从2013年至2018年迅速增加。中年患者更有可能感染NTM，特别是女性。分枝杆菌细胞内和细胞分枝杆菌/分枝杆菌脓肿是最常检测到的NTM病原体。 NTM的准确和及时鉴定对于诊断和治疗是重要的。

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