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首页> 外文期刊>Frontiers in Surgery >Urethral Lift as a Safe and Effective Procedure for Prostatic Hyplasia Population: A Systematic Review and Meta-Analysis
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Urethral Lift as a Safe and Effective Procedure for Prostatic Hyplasia Population: A Systematic Review and Meta-Analysis

机译：尿道升降机作为前列腺催风症人群的安全有效的程序：系统评价和荟萃分析

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Background: Prostatic urethral lift (PUL) is a relatively new minimally invasive treatment procedure for benign prostatic hyperplasia (BPH). In order to analyze the sustainability of this new protocol, a systematic review and meta-analysis is performed based on the published articles. Methods: We performed a critical review according to the preferred reporting items for systematic review and meta-analysis (PRISMA) and MOOSE guidelines. A total of 818 published articles matched our search terms, and 11 studies met the inclusion criteria. Data of each follow-up time point (1, 3, 6, 12, and 24 months) were analyzed in terms of baseline characteristics and functional and sexual health outcomes. The merged means of each time point were calculated using R package meta and shown in the tendency plot. Results: A total of 1,443 patients who underwent PUL are available for the research. At 24 months, the changes of the three indicators are statistically significant (IPSS 9.40 points, p 0.001; Qmax 3.39 ml/s, p 0.001; QoL 1.99 points, p 0.001) but were not as effective as TURP (from literature). The trend plot shows that, as time goes on, the effect of PUL tends to increase first and then weaken. Three items fitted a meaningful curve: IPSS (slope = ?1.378 t = ?12.395, p 0.001), Qmax (slope = ?1.382 t = ?6.429, p 0.001), and QoL (slope = ?0.218, t = ?10.058, p 0.001). Fitted curves of SHIM and PVR are not statistically significant. The regression reveals that IPSS, Qmax, and QoL could be predicted after accepting PUL. Conclusion: PUL appears to be a safe and effective procedure in selected patients with BPH and can improve the symptoms of urinary tract obstruction. However, it is not as effective as TURP and shows no influence to the objective indicators like PVR.
机译：背景：前列腺尿道升降机（PUL）是良性前列腺增生（BPH）的相对较新的微创治疗程序。为了分析这种新方案的可持续性，基于已发表的文章进行系统审查和元分析。方法：根据系统审查和META分析（PRISMA）和MOOSE指南的首选报告项目进行了批判性审查。共匹配818篇发表的文章，11项研究符合纳入标准。根据基线特征和功能性和性健康结果，分析了每个后续时间点（1,3,6,12和24个月）的数据。使用R包元计算每个时间点的合并装置，并在趋势图中显示。结果：共有1,443名接受普通患者的研究。在24个月时，三种指标的变化是统计学意义的（IPS 9.40点，P <0.001; Qmax 3.39ml / s，P <0.001; QOL 1.99点，P <0.001），但没有像土耳其人那样有效（来自文学）。趋势图表明，随着时间的推移，脉冲的效果倾向于先增加，然后削弱。三个项目拟合有意义的曲线：IPSS（斜率=？1.378 T =？12.395，P <0.001），Qmax（斜率=？1.382 T =Δ6.429，P <0.001），QOL（斜坡=？0.218，T =？10.058，p <0.001）。垫片和PVR的曲线没有统计学意义。回归揭示了IPS，Qmax和QoL可以在接受脉冲之后预测。结论：含量在BPH的选定患者中似乎是一种安全有效的程序，可以改善泌尿道梗阻的症状。然而，它与土盘不如PVR等目标指标没有影响。

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