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首页> 外文期刊>Quantitative Imaging in Medicine and Surgery >Optical coherence tomography angiography distortion correction in widefield montage images
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Optical coherence tomography angiography distortion correction in widefield montage images

机译：光学相干断层造影血管造影失真校正在阔地蒙太奇图像中

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Background: Optical coherence tomography (OCT) imaging is inherently susceptible to distortion artifacts due to the natural curvature of the eye. This study proposes a novel model for widefield OCT angiography (OCTA) distortion correction and analyzes the effects of this correction on quantification metrics. Methods: Widefield OCTA images were obtained on normal subjects at five fixation spatial positions. Radial and field distortion correction were applied and images stitched together to form a corrected widefield montage image. Vessel area density (VAD), vessel complexity index (VCI), and flow impairment area were quantified on the original and corrected montage images. Results: This model allows for distortion correction and montaging of widefield images. There were either statistically insignificant or small magnitude changes in vessel density and vessel complexity between uncorrected and corrected widefield images. There was a significant and large difference in flow impairment area, both in the macular (+8.2%, P=0.049) and peripheral areas (+17.2%, P=0.011), following correction. The relationship between pre- and post-correction flow impairment area was non-linear. Conclusions: Distortion correction of widefield OCTA images can result in clinically and statistically significant differences in important quantification metrics. This effect appears to be most pronounced in the periphery.
机译：背景：光学相干断层扫描（OCT）成像本质上是由于眼睛的自然曲率导致的变形伪像。本研究提出了一种新型景区OCT血管造影（OctA）失真校正的新型模型，并分析了这种校正对量化度量的影响。方法：在五个固定空间位置的正常受试者上获得宽Fifferocta图像。施加径向和场失真校正，并将图像缝合在一起以形成校正的宽场蒙太奇图像。血管区域密度（VAD），血管复杂性指数（VCI）和流量损伤区域在原始和校正的蒙太奇图像上量化。结果：该模型允许对Widefield图像进行失真校正和蒙营。在未校正和校正的宽场图像之间的血管密度和血管复杂性的血管密度和血管复杂性有统计学上微不足道或小。在校正后，在黄斑（+ 8.2％，P = 0.049）和外周区域（+ 17.2％，p = 0.011），均有显着且大小的差异。校正后和后校正后流动损伤区域之间的关系是非线性的。结论：阔地Octa图像的失真校正可能导致重要的量化指标的临床和统计学差异。这种效果似乎在外围最明显。

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