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Feasibility of and barriers to thalassemia screening in migrant populations: a cross-sectional study of Myanmar and Cambodian migrants in Thailand

机译:移民群体筛查的可行性和障碍:泰国缅甸和柬埔寨移民的横截面研究

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Thalassemia, an inherited hemoglobin disorder, has become a global public health problem due to population migration. Evidence-based strategies for thalassemia prevention in migrants are lacking. We characterized barriers to thalassemia screening and the burden of thalassemia in migrant workers in Thailand. Multilingual demographic and KAP surveys were completed by 197 Thai, 119 Myanmar, and 176 Cambodian adults residing in Thailand. Thalassemia awareness, socio-demographic predictors, and knowledge and attitude scores were compared between migrant and Thai subjects. Comprehensive thalassemia testing was performed for migrants. Migrants had extremely poor thalassemia awareness (4.1%) compared to Thai subjects (79.6%) and had lower thalassemia knowledge scores but similar attitude scores. Surveys identified differing sociodemographic factors predicting awareness in Thai and migrant subjects, as well as key misconceptions likely to hinder thalassemia screening uptake. Nearly all migrants consented to thalassemia testing. We identified abnormal hemoglobin profiles in 52.7% of migrants and a higher projected rate of severe thalassemia births in migrants. The high burden of thalassemia and tremendous knowledge gap in migrants needs urgent attention. Thalassemia screening was feasible and acceptable in our migrant population. Sociocultural and structural barriers merit further attention when designing thalassemia screening and prevention policies for migrants in Thailand and globally.
机译:遗传血红蛋白障碍血红蛋白障碍,由于人口迁移,已成为全球公共卫生问题。缺乏移民中的基于循证策略。我们以泰国的移民工人在泰国的境内筛选和中西血症的负担的障碍。多语种人口和KAP调查由197泰国,119名缅甸和居住在泰国的176名柬埔寨成年人完成。在移民和泰语科目之间比较了地名的认识,社会人口预测和知识和态度分数。对移民进行了综合的地中海贫血测试。与泰国科目(79.6%)相比,移民的地中海贫血人意识(4.1%)并降低了较低的地中海贫血知识分数,但相似的态度得分。调查确定了预测泰国和移民受试者的意识的不同的社会渗目因素,以及可能阻碍脑血症筛选的关键误解。几乎所有同意地中海贫血测试的移民。我们鉴定了52.7%的移民的异常血红蛋白谱,以及移民中严重的山西血症出生率的更高预定率。地中海贫血的高负担和移民的巨大知识差距需要紧急关注。在我们的移民人口中,地中海贫血筛查是可行和可接受的。社会文化和结构障碍在设计泰国和全球范围内的移民筛查和预防政策时,请进一步关注。

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