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The Understanding of Pediatric Akinetic Mutism

机译：对儿科的理解动力学

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Pediatric akinetic mutism syndrome is a clinical disease resulting from cerebellar injury and characterized by the absence of speech or reduced speech, emotional lability, there may also be hypotonia, oropharyngeal dysfunction/dysphagia, bladder and intestinal incontinence, or other behavioral disorders and neurological signals. It is described as the most recurrent complication in children, after posterior fossa tumor surgery, mainly related to cerebellar midline injuries. An increasing number of research and prospective reviews have provided valuable information on cerebellar mutism syndrome in recent years. The purpose of this review was to elucidate the pathophysiological basis and the predictive factors for this syndrome. Most cases of mutism are due to injury cerebellar tracts and cerebellar-cerebral circuits, involving particularly distinct points of the dentate-thalamus-cortical and dentato-rubro-thalamus-cortical. Advanced neuroimaging techniques, such as tractography and perfusion studies, have contributed to demonstrating changes in these pathways in patients with pediatric cerebellar mutism.
机译：儿科的特殊突变综合征是小脑损伤引起的临床疾病，其特征在于没有言语或缩减的言论，情绪萎靡，也可能存在低呼吸，口咽功能障碍/吞咽，膀胱和肠尿失禁，或其他行为障碍和神经系统。它被描述为儿童最常复发并发症，后窝肿瘤手术后，主要与小脑中线损伤有关。近年来，越来越多的研究和前瞻性评论提供了有关小脑突变综合征的宝贵信息。本评价的目的是阐明该综合征的病理生理基础和预测因素。大多数突变病例是由于损伤的小脑束和小脑 - 脑电路电路，涉及牙齿 - 丘脑 - 皮质和牙型 - rubro-thalamus-皮质的特别明显的点。先进的神经影像动物如牵引和灌注研究，有助于展示儿科小脑突变患者的这些途径的变化。

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