Cefiderocol treatment of Pseudomonas aeruginosa and extensively drug-resistant Acinetobacter baumannii retained spinal hardware infection causing reversible acute interstitial nephritis

Kimberly Cipko; Alice Kizny Gordon; Suman Adhikari; Pamela Konecny

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Cefiderocol treatment of Pseudomonas aeruginosa and extensively drug-resistant Acinetobacter baumannii retained spinal hardware infection causing reversible acute interstitial nephritis

机译：Pseudomonas铜绿假单胞菌的Cefiderocol治疗和广泛的耐药性传导杆菌保留脊柱硬件感染导致可逆急性间质性肾炎

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Infections with extensively drug-resistant Acinetobacter baumannii (XDRAB) have limited therapeutic options. We report successful salvage treatment of XDRAB and Pseudomonas aeruginosa -infected retained spinal hardware with cefiderocol, despite the development of reversible acute interstitial nephritis after 32 days of treatment.

机译：具有广泛的耐药性抗毒性杆菌（XDRAB）的感染具有有限的治疗选择。我们报告了XDRAB和假单胞菌铜绿假单胞菌的成功抢救治疗与Cefiderocol，尽管治疗32天后，尽管有逆转急性间质性肾炎的发展，但仍然具有Cefiderocol。

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《International journal of infectious diseases :》 |2021年第a期|共4页
作者
Kimberly Cipko; Alice Kizny Gordon; Suman Adhikari; Pamela Konecny;
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中图分类传染病;
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Extensively drug-resistant Acinetobacter baumannii (XDRAB)CefiderocolMDR Gram-negativeSpinal hardware infectionBiofilmAcute interstitial nephritisSurgical site infection;

机译：广泛的耐药性传导杆菌（XDRAB）Cefiderocolmdr克 - 否定阶硬件感染脑血管间质肾功能术部位感染;

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1. In vitro activities of cefiderocol, ceftolozane/tazobactam, ceftazidime/avibactam and other comparative drugs against imipenem-resistant Pseudomonas aeruginosa and Acinetobacter baumannii, and Stenotrophomonas maltophilia, all associated with bloodstreann infections in Taiwan [J] . Hsueh Shun-Chung, Lee Yuarn-Jang, Huang Yu-Tsung, The Journal of Antimicrobial Chemotherapy . 2019,第2期

机译：Cefiderocol，Ceftolozane / Tazobactam，Ceftazidime / Avibactam和其他对比药物抗性假单胞菌铜绿假单胞菌和嗜酸盐杆菌的其他比较药物的体外活动，以及史氏菌蛋白蛋白酶蛋白酶蛋白，麦芽糖疗法
2. Bloodstream infection caused by extensively drug-resistant Acinetobacter baumannii in cancer patients: high mortality associated with delayed treatment rather than with the degree of neutropenia [J] . Freire M. P., de Oliveira Garcia D., Garcia C. P., Clinical microbiology and infection: European Society of Clinical Microbiology and Infectious Diseases . 2016,第4期

机译：在癌症患者中抗毒性抗药性抗毒性抗毒性抗毒性的血流感染：与延迟治疗相关的高死亡率，而不是中性粒细胞减少
3. Comparison of the antibacterial effects of a short cationic peptide and 1% silver bioactive glass against extensively drug-resistant bacteria, Pseudomonas aeruginosa and Acinetobacter baumannii, isolated from burn patients [J] . Moghaddam Mehrdad Moosazadeh, Eftekhary Mohamad, Erfanimanesh Soroor, Amino acids . 2018,第11期

机译：短阳离子肽和1％银生物活性玻璃对广泛的耐药细菌，假单胞菌铜绿素和肺杆菌的抗菌作用的比较，烧伤患者分离出来
4. Long-Term Compassionate Use of Cefiderocol To Treat Chronic Osteomyelitis Caused by Extensively Drug-Resistant Pseudomonas aeruginosa and Extended-Spectrum-β-Lactamase-Producing Klebsiella pneumoniae in a Pediatric Patient [O] . Zain I. Alamarat, Jessica Babic, Truc T. Tran, 2020

机译：长期富有同情心的Cefiderocol治疗慢性骨髓炎在儿科患者中产生广泛的耐药假单胞菌铜绿假单胞菌和延长光谱 - β-内酰胺酶的肺炎群岛肺炎
5. Cefiderocol treatment of Pseudomonas aeruginosa and extensively drug-resistant Acinetobacter baumannii retained spinal hardware infection causing reversible acute interstitial nephritis [O] . Kimberly Cipko, Alice Kizny Gordon, Suman Adhikari, 2021

机译：Pseudomonas铜绿假单胞菌的Cefiderocol治疗和广泛的耐药性传导杆菌Baumannii保留脊柱硬件感染导致可逆的急性间质性肾炎

Cefiderocol treatment of Pseudomonas aeruginosa and extensively drug-resistant Acinetobacter baumannii retained spinal hardware infection causing reversible acute interstitial nephritis

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