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Electophoretically Deposition of Ti3C2 on Titanium Surface for Hard Tissue Implant Applications

机译:用于硬组织植入物应用的钛表面上的Ti3C2沉积。

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As a metallic biomaterial, titanium (Ti) exhibits excellent biocompatibility, but its osteoinductivity is limited. Therefore, to improve this property, an electrophoretic deposition (EPD) technique was used to coat the Ti surface with Ti3C2 MXene (Ti3C2), a new class of two-dimensional nanomaterial. Ti3C2 is known to have good biocompatibility and better osteoinductivity than graphene oxide. The coating layer was characterized by a particulate microstructure and exhibited X-ray diffraction and Raman spectroscopy peaks corresponding to the Ti3C2 phase. In vitro cell tests using human mesenchymal stem cells confirmed that the cell attachment and proliferation on Ti3C2-coated Ti were similar to that of bare Ti, and that the osteoinductivity was significantly enhanced compared with bare Ti.
机译:作为金属生物材料,钛(TI)表现出优异的生物相容性,但其骨诱导性受到限制。 因此,为了改善这种性质,使用电泳沉积(EPD)技术用Ti3C2 mxEn(Ti3C2)涂覆Ti表面,这是一种新的二维纳米材料。 已知Ti3C2具有良好的生物相容性和比石墨烯氧化物更好的骨诱导率。 涂层的特征在于颗粒状微观结构,并表现出与Ti3C2相对应的X射线衍射和拉曼光谱峰。 使用人间充质干细胞的体外细胞试验证实,Ti3C2涂覆的Ti上的细胞附着和增殖类似于裸TI的细胞附着和增殖,并且与裸机相比,骨诱导性显着增强。

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