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Glucose variability and mood in adults with diabetes: A systematic review

机译：糖尿病成年人的葡萄糖变异性和情绪：系统评价

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Aims To systematically review the literature regarding the association between glucose variability (GV) and mood in adults with diabetes, appraise the used methods and make suggestions for future research. Methods A systematic review of literature published up to May 2019 was performed. Abstracts and full texts were screened independently in duplicate. Experimental and observational studies reporting the association between GV and mood in adults with type 1 diabetes or type 2 diabetes were evaluated. A descriptive analysis of the extracted data was conducted, along with a quality assessment. Results Out of the 2.316 studies screened, eight studies met our criteria. Studies used a variety of measures and metrics to determine GV and mood. Four studies used continuous glucose monitoring (CGM). An association between GV and mood was found in four studies when correlating either postprandial glucose rate of increase with current mood or multiday GV with mood measured retrospectively. The other four studies did not find any association. Conclusions There is no clear empirical support for a link between GV and mood in adults with type 1 and type 2 diabetes. More rigorous research is warranted using CGM and ecological momentary assessment of mood to assess if and under what conditions an association between GV and mood exists.
机译：旨在系统地审查有关糖尿病成年人的葡萄糖变异性（GV）和情绪的关联的文献，评价使用的方法并提出未来研究的建议。方法对2019年5月发布的文学系统审查进行了系统审查。摘要和完整文本独立筛选重复筛选。评估了报告GV和1型糖尿病或2型糖尿病患者GV和情绪相关性的实验和观察研究。对提取数据进行了描述性分析，以及质量评估。结果筛选的2.316研究，八项研究达到了我们的标准。研究使用了各种措施和指标来确定GV和情绪。四项研究使用连续葡萄糖监测（CGM）。在四项研究中发现了GV和情绪之间的关联在与当前情绪或多个GV随着回顾性测量的心情而随着当前的情绪或多星期GV的相关性。另外四项研究没有找到任何关联。结论在1型和2型糖尿病中，GV和GV和情绪之间的联系没有明确的实证支持。使用CGM和生态瞬间评估情绪的生态瞬间评估更严格的研究，以评估GV和情绪之间的关联的条件。

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