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首页> 外文期刊>Endocrinology, Diabetes & Metabolism >Estimation of the prevalence of thyroid dysfunction in Catalonia through two different registries: Pharmaceutical dispensing and diagnostic registration
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Estimation of the prevalence of thyroid dysfunction in Catalonia through two different registries: Pharmaceutical dispensing and diagnostic registration

机译：通过两种不同注册评估估算加泰罗尼亚甲状腺功能障碍的患病率：药品分配和诊断登记

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Background Population studies on the prevalence of thyroid dysfunctions are costly. The pharmacy dispensing (PDR) and diagnosis (DR) registers allow us to study the epidemiology of these pathologies in a simpler way. Our aims: 1/Estimate the prevalence of thyroid dysfunction in Catalonia based on data from the PDR and the DR, 2/to evaluate the concordance of the results obtained by both strategies. Methods The population studied was the one registered with the public health system in Catalonia(Catsalut). In the PDR analysis, the information obtained through the Pharmaceutical Provision file (during 2012, 2013, 2014) was used regarding the number of patients under treatment (NPT) (levothyroxine and antithyroid medication). The DR analysis (2014) was performed by ICD‐9 codes (hyperthyroidism 242 and hypothyroidism 243, 244). Results According to the NPT in the PDR analysis, the prevalence of treated hypothyroidism increased over 3?years: 2.81%(2012), 2.92%(2013) and 3.07%(2014) ( P ?.00001). The prevalence of hyperthyroidism in treatment was 0.14%(2012), 0.13%(2013) and 0.14%(2014). According to the DR analysis in 2014, the prevalence of hypothyroidism was 2.54% and 0.35% for hyperthyroidism. The PDR analysis estimated a higher hypothyroidism prevalence compared to that estimated by the DR ( P ?.0001) and vice versa in the case of hyperthyroidism. Conclusion Both PDR and DR prevalence estimations of thyroid dysfunction show some degree of discordance probably due to undercoding bias in the case of DR and the absence of subclinical pathology in the case of PDR. However, both approaches are valid and complementary for estimating the prevalence of thyroid dysfunction.
机译：背景技术人口研究甲状腺功能障碍的患病率昂贵。药房分配（PDR）和诊断（DR）寄存器允许我们以更简单的方式研究这些病态的流行病学。我们的目标：1 /估计基于PDR和DR，2 /评估两种策略所获得的结果的一致性的基于PDRONIA的甲状腺功能障碍的患病率。方法研究人口是在加泰罗尼亚（Catsalut）的公共卫生系统注册的人口。在PDR分析中，通过药物拨款文件（2012年，2013年，2014年）获得的信息用于治疗（NPT）（左旋甲苯胺和亚甲状腺素药物）的患者数量。 DR分析（2014）由ICD-9代码（甲状腺功能亢进242和甲状腺功能亢进243,244）进行。结果根据不扩散核武器条约于PDR分析，经过治疗的甲状腺功能减退症的患病率超过3岁以下？年：2.81％（2012），2.92％（2013）和3.07％（2014）（P <。00001）。治疗中甲状腺功能亢进症的患病率为0.14％（2012），0.13％（2013）和0.14％（2014）。根据2014年的DR分析，甲状腺功能减退症的患病率为甲状腺功能亢进的患病率为2.54％和0.35％。与甲状腺功能亢进的情况下，PDR分析估计估计较高的甲状腺功能亢进患病率，并且在甲状腺功能亢进的情况下反之亦然。结论甲状腺功能障碍的PDR和博士患病率估算显示出一定程度的不间断，可能是由于在PDR的情况下博士的偏差和亚临床病理的缺失，因此可能是由于偏差。然而，两种方法都是有效和互补的，估计甲状腺功能障碍的患病率。

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