首页> 外文期刊>Endocrinology, Diabetes & Metabolism >Seasonal variations on endothelium‐dependent flow‐mediated vasodilation in adults with type 2 diabetes and nondiabetic adults with hypertension and/or dyslipidaemia who perform regular exercise
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Seasonal variations on endothelium‐dependent flow‐mediated vasodilation in adults with type 2 diabetes and nondiabetic adults with hypertension and/or dyslipidaemia who perform regular exercise

机译:患有2型糖尿病和非血糖成人的成人内皮依赖性流动介导的血管舒张的季节变异和进行定期运动的高血压和/或血脂血症

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Introduction:Endothelium-dependent flow-mediated dilation (FMD) of the brachial artery often changes seasonally. We aimed to examine the association between the seasonal variation on FMD and regular exercise in adults with type 2 diabetes (T2D) and nondiabetic adults with hypertension and/or dyslipidaemia (non-T2D).Methods:This retrospective study included 14 T2D and 17 non-T2D adults, who started to perform moderate-intensity aerobic exercise for 30-40?min/d at a hospital gym in 2006-2010 and maintained exercise performance at least 2?d/wk until the end of the observation period. We observed and analysed the data for 5?years (from March 2011 to February 2016). FMD, cardio-ankle vascular index (CAVI) and metabolic outcomes were compared among seasons in the T2D and non-T2D groups.Results:The FMD values were lower in winter than in other seasons in both groups (all P??.01). The annual range of FMD was larger by 31% in the T2D group than in the non-T2D group (P??.05). The systolic blood pressure (BP) values were higher in winter than in other seasons in both groups (all P??.01), and the diastolic BP values were higher in winter than in summer in both groups (T2D: P??.05; non-T2D: P??.01). CAVI and other outcomes did not change seasonally.Conclusions:Flow-mediated vasodilation showed seasonal variation in T2D adults, even if they performed exercise regularly for a long period of time. Additionally, we found that the annual range of FMD might increase with the presence of T2D.? 2020 The Authors. Endocrinology, Diabetes & Metabolism published by John Wiley & Sons Ltd.
机译:简介:肱动脉的内皮依赖性流动介导的扩张(FMD)经常变化。我们旨在审查与2型糖尿病(T2D)和NongiaBete成人的成年人季节性变化与患有高血压和/或血脂血症(非T2D)的常规运动之间的关联。方法:这个回顾性研究包括14 T2D和17非-T2D成年人,他们在2006 - 2010年在医院健身房开始进行中等强度有氧运动,在医院健身房进行30-40次,并在观察期结束时保持运动性能至少2?D / WK。我们观察并分析了5年(从2011年3月至2016年2月)的数据。在T2D和非T2D组的季节中比较了FMD,心脏踝血管指数(CAVI)和代谢结果。结果:冬季FMD值比两组的其他季节(所有P≤1; 01)。 T2D组的每年FMD的年度范围比非T2D组在T2D组中较大31%(P?& 05)。冬季的收缩压(BP)值高于两组中的其他季节(所有p≤01),冬季舒张性BP值比两组夏季更高(T2D:P? &?。05;非T2D:P?&Δ01)。 Cavi和其他结果并没有季节性改变。结论:流动介导的血管舒张显示出T2D成人的季节变化,即使它们在很长一段时间内经常进行锻炼。此外,我们发现,在T2D的存在下,FMD的年度范围可能会增加。? 2020作者。 John Wiley&Sons Ltd.出版的内分泌,糖尿病和新陈代谢

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