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首页> 外文期刊>Endocrinology, Diabetes & Metabolism >Outcomes for continuous subcutaneous insulin infusion users in young adults from lower socioeconomic backgrounds
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Outcomes for continuous subcutaneous insulin infusion users in young adults from lower socioeconomic backgrounds

机译：来自较低社会经济背景的年轻成年人的连续皮下胰岛素输注用户的结果

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Objective Diabetes technology is available and its efficacy and safety have been demonstrated; however, there is little evidence as to how this technology is being utilized and its effectiveness in vulnerable populations. This study evaluated differences in outcomes for young adults in the United States (U.S.) from lower socioeconomic (SES) backgrounds with type 1 diabetes (T1D) managed on continuous subcutaneous insulin infusion (CSII) versus multiple daily injections (MDI) or fixed-dose insulin (FDI). Research design, methods and participants Utilizing the Optum? de-identified Electronic Health Record data set between 2008 and 2018 to perform a retrospective, cohort study, we identified 805 subjects with T1D aged 18–30?years with Medicaid. We evaluated median difference in HbA1c between CSII and MDI/FDI users for 24?months. Predictors of diabetic ketoacidosis (DKA)-associated hospitalizations by CSII use were evaluated using logistic regression. Results CSII users showed statistically significant lower median HbA1c values at 24?months of follow-up compared to individuals on MDI/FDI. Non-white individuals were at lower odds of receiving treatment with CSII. Subjects on CSII were not more likely to be hospitalized for DKA compared to subjects treated with MDI/FDI. Older subjects were at lower odds of being hospitalized for DKA. Males and subjects followed by Endocrinologists were at higher odds of being hospitalized for DKA. Conclusions Young adults with T1D from lower SES backgrounds show improved glycaemic control when in CSII compared to MDI/FDI without increases in hospitalizations for DKA.
机译：客观糖尿病技术可用，并证明了其疗效和安全性;但是，几乎没有证据表明如何在弱势群体中使用这种技术以及其在弱势群体中的有效性。本研究评估了美国（美国）与患有1型糖尿病（T1D）的美国患者（SES）背景的年轻成年人结果的差异（CSII）与多种日常注射（MDI）或固定剂量胰岛素（FDI）。利用optum的研究，方法和参与者？在2008年至2018年之间进行了去识别的电子健康记录数据，以执行回顾性，队列队列研究，我们确定了805名受试者，T1D为18-30岁的T1D？多年的医疗补助。我们在CSII和MDI / FDI用户之间的24个月之间评估了HBA1C的中位数差异。使用Logistic回归评估CSII使用的糖尿病酮症中的预测因子（DKA） - 通过CSII使用的住院治疗。结果CSII用户在MDI / FDI上的个体上显示了24个月的24个月的统计学显着的下位数HBA1C值。非白色个体均较低，含有CSII治疗的几率。与用MDI / FDI治疗的受试者相比，CSII的受试者并不容易住院DKA。较老的科目较低的几率为DKA住院。人民学家随后的男性和受试者均可在为DKA住院的几率较高。结论较低的SES背景中具有T1D的年轻成人显示在CSII中显示出改善的血糖控制与MDI / FDI相比，DKA的住院治疗不增加。

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